What Do Medicinal Chemists Actually Make? A 50-Year Retrospective

被引：292
|
作者：
Walters, W. Patrick [1 ]
Green, Jeremy [1 ]
Weiss, Jonathan R. [1 ]
Murcko, Mark A. [1 ]
机构：
[1] Vertex Pharmaceut Inc, Cambridge, MA 02139 USA
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 2011年 / 54卷 / 19期
关键词：
POLAR MOLECULAR-SURFACE; ATOM-ADDITIVE METHOD; DRUG DISCOVERY; ORAL BIOAVAILABILITY; AQUEOUS SOLUBILITY; PARTITION-COEFFICIENTS; INTESTINAL-ABSORPTION; TRANSPORT PHENOMENA; LIGAND EFFICIENCY; RAPID CALCULATION;
D O I：
10.1021/jm200504p
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：6405 / 6416
页数：12
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