What Do Medicinal Chemists Actually Make? A 50-Year Retrospective

被引：292

作者：

Walters, W. Patrick ^{[1
]}

Green, Jeremy ^{[1
]}

Weiss, Jonathan R. ^{[1
]}

Murcko, Mark A. ^{[1
]}

机构：

[1] Vertex Pharmaceut Inc, Cambridge, MA 02139 USA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 2011年 / 54卷 / 19期

关键词：

POLAR MOLECULAR-SURFACE; ATOM-ADDITIVE METHOD; DRUG DISCOVERY; ORAL BIOAVAILABILITY; AQUEOUS SOLUBILITY; PARTITION-COEFFICIENTS; INTESTINAL-ABSORPTION; TRANSPORT PHENOMENA; LIGAND EFFICIENCY; RAPID CALCULATION;

D O I：

10.1021/jm200504p

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：6405 / 6416

页数：12

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