Versatile and scalable fabrication method for laser-generated focused ultrasound transducers

被引:10
|
作者
Aytac-Kipergil, E. [1 ,2 ]
Alles, E. J. [1 ,2 ]
Pauw, H. C. [1 ]
Karia, J. [1 ]
Noimark, S. [1 ,2 ]
Desjardins, A. E. [1 ,2 ]
机构
[1] UCL, Dept Med Phys & Biomed Engn, Malet Pl Engn Bldg, London WC1E 6BT, England
[2] UCL, Wellcome EPSRC Ctr Intervent & Surg Sci, Charles Bell House,43-45 Foley St, London W1W 7TY, England
基金
英国工程与自然科学研究理事会; 英国惠康基金;
关键词
NANOPARTICLES; DELIVERY; FIELDS;
D O I
10.1364/OL.44.006005
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A versatile and scalable fabrication method for laser-generated focused ultrasound transducers is proposed. The method is based on stamping a coated negative mold onto polydimethylsiloxane, and it can be adapted to include different optical absorbers that are directly transferred or synthesized in situ. Transducers with a range of sizes down to 3 mm in diameter are presented, incorporating two carbonaceous (multiwalled carbon nanoparticles and candle soot nanoparticles) and one plasmonic (gold nanoparticles) optically absorbing component. The fabricated transducers operate at central frequencies in the vicinity of 10 MHz with bandwidths in the range of 15-20 MHz. A transducer with a diameter of 5 mm was found to generate a positive peak pressure greater than 35 MPa in the focal zone with a tight focal spot of 150 pm in lateral width. Ultrasound cavitation on the tip of an optical fiber was demonstrated in water for a transducer with a diameter as small as 3 mm. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License.
引用
收藏
页码:6005 / 6008
页数:4
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