Hormonal and Nonhormonal Treatment of Vasomotor Symptoms

被引：28

作者：

Krause, Miriam S. ^{[1
]}

Nakajima, Steven T. ^{[2
]}

机构：

[1] Fertil & Endocrine Associates, Louisville, KY 40207 USA

[2] Stanford Fertil & Reprod Med Ctr, Palo Alto, CA 94304 USA

来源：

OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA | 2015年 / 42卷 / 01期

关键词：

Menopause; Vasomotor symptoms; Estrogen; Progestogen; SSRI; SNRI; POSTMENOPAUSAL WOMEN; HOT FLASHES; MENOPAUSAL SYMPTOMS; BLACK COHOSH; REPLACEMENT THERAPY; ESTROGEN THERAPY; VAGINAL ATROPHY; PLACEBO; MANAGEMENT; ESTRADIOL;

D O I：

10.1016/j.ogc.2014.09.008

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

This article focuses on the cause, pathophysiology, differential diagnosis of, and treatment options for vasomotor symptoms. In addition, it summarizes important points for health care providers caring for perimenopausal and postmenopausal women with regard to health maintenance, osteoporosis, cardiovascular disease, and vaginal atrophy. Treatment options for hot flashes with variable effectiveness include systemic hormone therapy (estrogen/progestogen), nonhormonal pharmacologic therapies (selective serotonin reuptake inhibitors, selective norepinephrine reuptake inhibitors, clonidine, gabapentin), and nonpharmacologic therapy options (behavioral changes, acupuncture). Risks and benefits as well as contraindications for hormone therapy are further discussed.

引用

页码：163 / +

页数：19

共 50 条

[21] Anxiety Predicts Reduction in Menopausal Vasomotor Symptoms with Hormonal and Non-Hormonal Treatments
Cohen, Lee S.
Soares, Claudio N.
Pasciullo, Erica
Silver, Michael
Joffe, Hadine
[J]. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2008, 15 (06): : 1228 - 1228
[22] Does purified Swedish pollen extract, a nonhormonal treatment for vasomotor symptoms, inhibit the CYP2D6 enzyme system?
Goldstein, Steven R.
Espie, Marc
Druckmann, Rene
[J]. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2015, 22 (11): : 1212 - 1214
[23] HORMONAL AND NONHORMONAL CONTROL OF GLYCOGEN METABOLISM
LARNER, J
[J]. TRANSACTIONS OF THE NEW YORK ACADEMY OF SCIENCES, 1966, 29 (02): : 192 - &
[24] Exercise for Treatment of the Vasomotor Symptoms of Menopause
Fogleman, Corey D.
[J]. AMERICAN FAMILY PHYSICIAN, 2012, 85 (03) : 237 - 237
[25] Vasomotor symptoms in menopause - diagnostic and treatment
Sobstyl, Malgorzata
Bednarek, Wieslawa
Tkaczuk-Wlach, Joanna
Sobsty, Jacek
Jakiel, Grzegorz
[J]. MENOPAUSE REVIEW-PRZEGLAD MENOPAUZALNY, 2011, 10 (03): : 254 - 258
[26] HORMONAL AND NONHORMONAL CYTOPROTECTIVE EFFECT BY SOMATOSTATINS
USADEL, KH
[J]. HORMONE RESEARCH, 1988, 29 (2-3) : 83 - 85
[27] Treatment of vasomotor symptoms during perimenopause
Desindes, S
[J]. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2004, 11 (01): : 2 - 4
[28] Non-hormonal management of menopausal vasomotor symptoms: Psychosocial interventions
Mintziori, Gesthimani
Goulis, Dimitrios G.
Lambrinoudaki, Irene
Ceausu, Iuliana
Depypere, Herman
Erel, C. Tamer
Perez-Lopez, Faustino R.
Schenck-Gustafsson, Karin
Simoncini, Tommaso
Tremollieres, Florence
Rees, Margaret
[J]. MATURITAS, 2015, 82 (04) : 444 - 445
[29] Nonhormonal management of menopause-associated vasomotor symptoms: 2015 position statement of The North American Menopause Society
Carpenter, Janet
Gass, Margery L. S.
Maki, Pauline M.
Newton, Katherine M.
Pinkerton, JoAnn V.
Taylor, Maida
Utian, Wulf H.
Schnatz, Peter F.
Kaunitz, Andrew M.
Shapiro, Marla
Shifren, Jan L.
Hodis, Howard N.
Kingsberg, Sheryl A.
Liu, James H.
Richard-Davis, Gloria
Santoro, Nanette
Sievert, Lynnette Leidy
Schiff, Isaac
Pike, Caitlin
Allen, Penny
[J]. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2015, 22 (11): : 1155 - 1174
[30] MUTUAL ADDITIVITY OF HORMONAL AND NONHORMONAL STIMULATION OF GLUCONEOGENESIS
KUMMEL, L
[J]. BIOCHEMISTRY INTERNATIONAL, 1987, 14 (05): : 815 - 821

← 1 2 3 4 5 →