Networks of workstations (NOWs), which are generally composed of autonomous compute elements networked together, axe an attractive parallel computing platform since they offer high performance at low cost. The autonomous nature of the environment, however, often results in inefficient utilization due to load imbalances caused by three primary factors: 1) unequal load (compute or communication) assignment to equally-powerful compute nodes, 2) unequal resources at compute nodes, and 3) multiprogramming. These load imbalances result in idle waiting time on cooperating processes that need to synchronize or communicate data. Additional waiting time may result due to local scheduling decisions in a multiprogrammed environment. In this paper, we present a combined approach of compile-time analysis, run-time load distribution, and operating system scheduler cooperation for improved utilization of available resources in an autonomous NOW. The techniques we propose allow efficient resource utilization by taking into consideration all three causes of load imbalance in addition to locality of access in the process of load distribution. The resulting adaptive load distribution and cooperative scheduling system allows applications to take advantage of parallel resources when available by providing better performance than when the loaded resources axe not used at all.