Effect of de-noising and DDRV correction on cone-beam SPECT reconstruction with non-uniform attenuation

被引：0

作者：

Zhang, Hao ^{[1
]}

Wen, Junhai ^{[1
]}

Yin, Wen ^{[2
]}

Li, Cuifen ^{[1
]}

Zhang, Kangping ^{[1
]}

Liang, Zhengrong ^{[3
]}

机构：

[1] Beijing Inst Technol, Sch Life Sci & Technol, Dept Biomed Engn, Beijing 100081, Peoples R China

[2] Beijing Univ Technol, Sch Software Engn, Beijing, Peoples R China

[3] SUNY Stony Brook, Dept Radiol, Stony Brook, NY 11794 USA

来源：

MEDICAL IMAGING 2011: PHYSICS OF MEDICAL IMAGING | 2011年 / 7961卷

基金：

中国国家自然科学基金;

关键词：

SPECT; cone-beam; reconstruction; Poisson noise; DDRV; non-uniform attenuation;

D O I：

10.1117/12.877352

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

SPECT (single photon emission computed tomography) is a non-invasive, cost-effective means for assessment of tissue/organ functions in nuclear medicine. For more accurate diagnosis, quantitative reconstruction of radiotracer concentration at any location inside the body is desired. To achieve this goal, we have to address a number of factors that significantly degrade the acquired projection data. The cone-beam SPECT system has higher resolution comparing with parallel-beam and fan-beam SPECT, which is highly advantageous in small object detection. In this paper, we used four analytical reconstruction schemes for cone-beam SPECT that allow simultaneous compensation for non-uniform attenuation and distance-dependent resolution variation (DDRV), as well as accurate treatment of Poisson noise. The simulation results show that the reconstruction scheme 1 and 4 both can obtain good reconstruction results.

引用

页数：8

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