Chronic Obstructive Pulmonary Disease (COPD) constitutes 30% of cases in chest clinics and accounts for 1 to 2.5% admissions in hospitals all over India. COPD is a spectrum of disorders that results in air flow obstruction. Precise role of bacteria will help the clinical practitioner in managing COPD cases effectively. Early morning sputum samples were obtained from the patients. Bacterial identification and its antibiogram were done by standard conventional methods. Incidence of COPD was 4.33% with male of female ratio 2.95:1. Pathogenic bacteria were isolated in 195 samples (72.5%) whereas commensals were isolated in 74 samples (27.5%). Among the 195 samples, single bacteria were isolated in 187 samples and in 8 samples polymicrobial etiology were noted. Bacterial infection in Chronic Obstructive Pulmonary Disease is a major cause of morbidity and mortality in both the developed and developing countries. The bacteriological profile COPD is constantly changing with advanced diagnostic techniques. The bacterial isolation rate also improved due to appropriate sample collection and Bartlett's grading of sputum. Knowledge of the microorganisms in COPD along with their antibiotic sensitivity pattern will help in selecting suitable antibiotics for treating these infections and preventing mortality.
机构:
Univ Calif San Francisco, Div Pulm Crit Care Allergy & Sleep Med, San Francisco, CA 94143 USAUniv Calif San Francisco, Div Pulm Crit Care Allergy & Sleep Med, San Francisco, CA 94143 USA
Christenson, Stephanie A.
Smith, Benjamin M.
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Columbia Univ, Dept Med, Med Ctr, New York, NY USA
McGill Univ, Dept Med, Hlth Ctr, Montreal, PQ, CanadaUniv Calif San Francisco, Div Pulm Crit Care Allergy & Sleep Med, San Francisco, CA 94143 USA
Smith, Benjamin M.
Bafadhel, Mona
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Kings Coll London, Sch Immunol & Microbial Sci, Fac Life Sci & Med, London, England
Univ Oxford, Dept Resp Med, Nuffield Dept Med, Oxford, EnglandUniv Calif San Francisco, Div Pulm Crit Care Allergy & Sleep Med, San Francisco, CA 94143 USA
Bafadhel, Mona
Putcha, Nirupama
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Johns Hopkins Univ, Sch Med, Div Pulm & Crit Care Med, Baltimore, MD 21224 USAUniv Calif San Francisco, Div Pulm Crit Care Allergy & Sleep Med, San Francisco, CA 94143 USA
机构:
Duke Univ, Med Ctr, Dept Med, Div Pulm Allergy & Crit Care Med, Durham, NC 27710 USADuke Univ, Med Ctr, Dept Med, Div Pulm Allergy & Crit Care Med, Durham, NC 27710 USA