Treatment of opioid dependence with buprenorphine: current update

被引：0
|
作者：
Soyka, Michael [1 ,2 ]
机构：
[1] Med Pk Chiemseeblick, Rasthausstr 25, D-83233 Bernau, Germany
[2] Univ Munich, Psychiat Hosp, Munich, Germany
来源：
DIALOGUES IN CLINICAL NEUROSCIENCE | 2017年 / 19卷 / 03期
关键词：
buprenorphine; methadone; opioid; opioid dependence; outcome; treatment; NATIONALLY-REPRESENTATIVE-COHORT; METHADONE-MAINTENANCE TREATMENT; SUBSTANCE USE; PSYCHOSOCIAL INTERVENTIONS; SUBSTITUTION TREATMENT; HEROIN DEPENDENCE; MORTALITY-RATES; UNITED-STATES; RETENTION; THERAPY;
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Opioid maintenance treatment is the first-line approach in opioid dependence. Both the full opioid agonist methadone (MET) and the partial agonist buprenorphine (BUP) are licensed for the treatment of opioid dependence. BUP differs significantly from MET in its pharmacology, side effects, and safety issues. For example, the risk of respiratory depression is lower than with MET. The risk of diversion and injection of BUP have been reduced by also making it available as a tablet containing the opioid antagonist naloxone. This review summarizes the clinical effects of BUP and examines possible factors that can support decisions regarding the use of BUP or MET in opioid-dependent people. (C) 2017, AICH - Servier Research Group
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页码：299 / +
页数：11
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