New chiral NMR shift reagent for α-amino acids and N-protected oligopeptides in aqueous solution

被引：16
|
作者：
Watanabe, M [1 ]
Hasegawa, T [1 ]
Miyake, H [1 ]
Kojima, Y [1 ]
机构：
[1] Osaka City Univ, Dept Chem, Grad Sch Sci, Sumiyoshi Ku, Osaka 5588585, Japan
来源：
CHEMISTRY LETTERS | 2001年 / 01期
关键词：
D O I：
10.1246/cl.2001.4
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A europium(III) complex with a new chiral ligand, N,N-bis[2-{N-methyl((1S)-1-carboxy-3-methyl) butylamino}ethyl]-glycine, is described as a new chiral shift reagent for cr-amino acids and N-acyl-oligopeptides in aqueous solutions without signal broadening on high resolution NMR spectroscopy. In addition, the molecular structure of lanthanum(III) complex with this ligand is revealed by X-ray crystallography.
引用
收藏
页码：4 / 5
页数：2
相关论文
共 50 条
  • [21] SYNTHESIS OF ACTIVATED ESTERS OF N-PROTECTED AMINO-ACIDS
    WOLMAN, Y
    LADKANY, D
    FRANKEL, M
    JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1967, (08): : 689 - &
  • [22] PAPAIN CATALYZED ESTERIFICATION OF N-PROTECTED AMINO-ACIDS
    CHEN, ST
    WANG, KT
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1988, (04) : 327 - 328
  • [23] SILVER(I) COMPLEXES WITH N-PROTECTED AMINO-ACIDS
    ANTOLINI, L
    MENABUE, L
    SALADINI, M
    MORINI, P
    INORGANICA CHIMICA ACTA-BIOINORGANIC CHEMISTRY, 1980, 46 (04): : L77 - L78
  • [24] REARRANGEMENT OF DIACYLAMINES CONTAINING N-PROTECTED AMINO-ACIDS
    GRUSZECKI, W
    GRUSZECKA, M
    BRADACZEK, H
    LIEBIGS ANNALEN DER CHEMIE, 1987, (05): : 483 - 484
  • [25] Use of N-protected amino acids in the minisci radical alkylation
    Cowden, CJ
    ORGANIC LETTERS, 2003, 5 (23) : 4497 - 4499
  • [26] A 2,3-butanedione protected chiral glycine equivalent -: a new building block for the stereoselective synthesis of enantiopure N-protected α-amino acids
    Dixon, DJ
    Harding, CI
    Ley, SV
    Tilbrook, DMG
    CHEMICAL COMMUNICATIONS, 2003, (04) : 468 - 469
  • [27] Solventless Synthesis of N-Protected Amino Acids in a Ball Mill
    Konnert, Laure
    Gauliard, Anne
    Lamaty, Frederic
    Martinez, Jean
    Colacino, Evelina
    ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2013, 1 (09): : 1186 - 1191
  • [28] Kinetic regularities of resolution of amines racemates in the acylation reaction with chiral N-protected amino acids esters
    Bakhtin, Stanislav
    Sinelnikova, Marina
    INTERNATIONAL JOURNAL OF CHEMICAL KINETICS, 2023, 55 (11) : 743 - 750
  • [29] Synthesis of new fluorescent pyrylium dyes and study of their interaction with N-protected amino acids
    Beltran, Alicia
    Burguete, M. Isabel
    Galindo, Francisco
    Luis, Santiago V.
    NEW JOURNAL OF CHEMISTRY, 2020, 44 (22) : 9509 - 9521
  • [30] HIGHLY CONSISTENT CORRELATION BETWEEN ABSOLUTE-CONFIGURATION OF ALPHA-AMINO-ACIDS AND THEIR SHIFT INDUCED BY THE NMR CHIRAL SHIFT-REAGENT PROPYLENEDIAMINETETRAACETATOEUROPIUM(III) IN AQUEOUS-SOLUTION
    KABUTO, K
    SASAKI, Y
    JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (09) : 670 - 671
12345