A case report of Meige syndrome-like blepharospasm caused by ingestion of allopurinol

被引：0
|
作者：
Luo LaiMin [1 ]
机构：
[1] Nanchang Univ, Dept Nephrol, Affiliated Hosp 1, Yongwai St, Nanchang, Jiangxi, Peoples R China
来源：
PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2020年 / 33卷 / 04期
关键词：
Allopurinol; Meige-syndrome; diagnosis; pathogenesis; DOPAMINE INTERACTIONS; PATHOPHYSIOLOGY; EXPRESSION; TORSINA;
D O I：
10.36721/PJPS.2020.33.4.REG.1707-1709.1
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
One case of allopurinol-caused rare adverse reactions was reported. One male 51-year-old patient presented blurred vision, streaming eyes, photophobia and blepharospasm sequentially 1 week after oral administration of allopurinol. Complete remission was obtained after Botulinum toxin was locally injected. Allopurinol may cause Meige syndrome-like blepharospasm, the mechanism of which may be related to the inhibition of dopamine activity by affecting adenosine level in the brain.
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页码：1707 / 1709
页数：3
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