Autoimmune thrombocytopenia in non-Hodgkin's lymphomas

被引：67
|
作者：
Hauswirth, Alexander W. [1 ]
Skrabs, Cathrin [1 ]
Schuetzinger, Christian [1 ]
Raderer, Markus [2 ]
Chott, Andreas [3 ]
Valent, Peter [1 ]
Lechner, Klaus [1 ]
Jaeger, Ulrich [1 ]
机构：
[1] Med Univ Vienna, Dept Med 1, Div Hematol & Hemostaseol, Wahringergurtel 18-20, A-1090 Vienna, Austria
[2] Med Univ Vienna, Oncol, Vienna, Austria
[3] Med Univ Vienna, Dept Pathol, Vienna, Austria
来源：
HAEMATOLOGICA | 2008年 / 93卷 / 03期
关键词：
autoimmune thrombocytopenias; non-Hodgkin's lymphoma;
D O I：
10.3324/haematol.11934
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Autoimmune thrombocytopenia is a common immune-hematologic complication in non-Hodgkin's lymphomas and may complicate the treatment. We analyzed an original series from our institute as well as published cases of non-Hodgkin's lymphomas (excluding chronic lymphocytic leukemia) associated with autoimmune thrombocytopenia with regard to demographic factors, prevalence in non-Hodgkin's lymphoma subtypes and treatment outcome. The male/female ratio is 1.75. Half of the cases occurred prior to diagnosis of lymphoma. Chemotherapy is the best treatment in many non-Hodgkin's lymphomas patients with autoimmune thrombocytopenia compared with standard treatment of autoimmune thrombocytopenia. Splenectomy is effective in splenic marginal zone lymphoma. Autoimmune thrombocytopenia in patients with non-Hodgkin's lymphomas is potentially life-threatening and difficult to treat.
引用
收藏
页码：447 / 450
页数：4
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