Clinical Significance and Therapeutic Management of Weight Loss in Patients With Idiopathic Intracranial Hypertension

被引：0
|
作者：
Hoffmann, Jan [1 ,2 ]
机构：
[1] Kings Coll London, Inst Psychiat Psychol & Neurosci, Wolfson Ctr Age Related Dis, London, England
[2] Kings Coll Hosp London, NIHR Wellcome Trust Kings Clin Res Facil, SLaM Biomed Res Ctr, London, England
来源：
NEUROLOGY | 2022年 / 99卷 / 11期
关键词：
D O I：
10.1212/WNL.0000000000201076
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Obesity is a diagnostic hallmark of idiopathic intracranial hypertension (IIH).1,2 A significant body of evidence indicates that beyond being comorbid conditions, in many patients obesity plays a causal role in the pathophysiology of IIH.3 Numerous studies show that body weight influences intracranial pressure (ICP) and the symptom severity of IIH.4,5 Based on this evidence, 2 clinical trials evaluating the influence of weight loss on the clinical course of IIH have been completed.6,7 Although the trials were both uncontrolled, the results convincingly showed that obesity and IIH are causally linked, and that active weight loss would be an effective treatment strategy. © 2022 American Academy of Neurology.
引用
收藏
页码：451 / 452
页数：2
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