Practical Considerations for Ketogenic Diet in Adults With Super-Refractory Status Epilepticus

被引：5

作者：

Kaul, Neha ^{[1
,2
,3
,4
,5
,6
]}

Laing, Joshua ^{[5
,6
]}

Nicolo, John-Paul ^{[3
,4
,5
,6
]}

Nation, Judy ^{[3
,4
]}

Kwan, Patrick ^{[3
,4
,5
,6
]}

O'Brien, Terence J. ^{[3
,4
,5
,6
]}

机构：

[1] Royal Melbourne Hosp, Dept Allied Hlth Clin Nutr, Melbourne, Vic, Australia

[2] Alfred Hosp, Dept Nutr & Dietet, Melbourne, Vic, Australia

[3] Univ Melbourne, Royal Melbourne Hosp, Dept Med, Melbourne, Vic, Australia

[4] Univ Melbourne, Royal Melbourne Hosp, Dept Neurol, Melbourne, Vic, Australia

[5] Alfred Hosp, Dept Neurosci, Melbourne, Vic, Australia

[6] Monash Univ, Melbourne, Vic, Australia

来源：

NEUROLOGY-CLINICAL PRACTICE | 2021年 / 11卷 / 05期

基金：

英国医学研究理事会; 澳大利亚国家健康与医学研究理事会;

关键词：

CONVULSIVE STATUS EPILEPTICUS; MEDIUM-CHAIN TRIGLYCERIDES; PROPOFOL INFUSION SYNDROME; THERAPY; RECOMMENDATIONS; GUIDELINES; CHILDREN;

D O I：

10.1212/CPJ.0000000000001009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Purpose of Review Ketogenic diet therapy can be used as an adjuvant treatment of super-refractory status epilepticus (SRSE). However, the drug and metabolic interactions with concomitant treatments present a challenge for clinicians. In this review, we focus on the practical considerations of implementing ketogenic dietary therapy in the acute setting, including the dietary composition, potential drug-diet interactions, and monitoring during ketogenic treatment. Recent Findings This report describes the ketogenic diet therapy protocol implemented for the treatment of SRSE and a review of the current evidence to support clinical practice. Summary The control of SRSE is critical in reducing morbidity and mortality. There is emerging evidence that ketogenic diet may be a safe and effective treatment option for these patients.

引用

页码：438 / 444

页数：7

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