Incidence and Geographic Distribution of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal Province, South Africa

被引：12
|
作者：
Lim, Jennifer R. [1 ,2 ]
Gandhi, Neel R. [1 ,2 ,3 ]
Mthiyane, Thuli [4 ]
Mlisana, Koleka [4 ,5 ]
Moodley, Julie [5 ]
Jaglal, Prenika [5 ]
Ramdin, Neeshan [6 ]
Brust, James C. M. [1 ,2 ]
Ismail, Nazir [6 ,7 ]
Rustomjee, Roxana [8 ]
Shah, N. Sarita [1 ,2 ]
机构：
[1] Albert Einstein Coll Med, Bronx, NY 10467 USA
[2] Montefiore Med Ctr, Bronx, NY 10467 USA
[3] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA
[4] Univ KwaZulu Natal, Durban, South Africa
[5] Natl Hlth Lab Serv, Durban, South Africa
[6] Natl Inst Communicable Dis, Ctr TB, Natl Hlth Lab Serv, Johannesburg, South Africa
[7] Univ Pretoria, Dept Med Microbiol, ZA-0002 Pretoria, South Africa
[8] MRC, Cape Town, South Africa
来源：
PLOS ONE | 2015年 / 10卷 / 07期
基金：
美国国家卫生研究院;
关键词：
OUTCOMES;
D O I：
10.1371/journal.pone.0132076
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
South Africa is experiencing a widespread drug-resistant tuberculosis epidemic, although data are limited regarding the current situation. This study finds that the extensively drugr-esistant tuberculosis (XDR-TB) incidence in KwaZulu-Natal increased to 3.5 cases/100,000 (776 cases) in 2011-2012. XDR-TB cases are widely distributed geographically, with the majority of districts experiencing a rise in incidence.
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页数：7
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