Affinity selection-mass spectrometry screening: Development and validation of a 384-well ultrafiltration format for drug discovery

被引:0
|
作者
Williamson, Robert [1 ]
Terry, David [1 ]
Roth, Gregory [2 ]
机构
[1] Sanford Burnham Med Res Inst, Pharmacol, Orlando, FL USA
[2] Sanford Burnham Med Res Inst, Orlando, FL USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
348
引用
收藏
页数:1
相关论文
共 33 条
  • [21] Development of drug discovery screening system by molecular interaction kinetics-mass spectrometry
    Obi, Naoko
    Fukuda, Tetsuya
    Nakayama, Noboru
    Ervin, John
    Bando, Yasuhiko
    Nishimura, Toshihide
    Nagatoishi, Satoru
    Tsumoto, Kouhei
    Kawamura, Takeshi
    RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2018, 32 (08) : 665 - 671
  • [22] High-throughput screening, "protein-metabolite" interaction, and hypoglycemic effect investigations of α-amylase inhibitors in teas using an affinity selection-mass spectrometry method
    Wang, Zhe
    Gao, Jianjian
    Zhao, Yanni
    Zhou, Mengxue
    Chen, Dan
    Zhou, Chuang
    Yu, Shuai
    Lin, Zhiyuan
    Peng, Jiakun
    Lin, Zhi
    Dai, Weidong
    LWT-FOOD SCIENCE AND TECHNOLOGY, 2024, 203
  • [23] A "No-Touch" Antibody-Staining Method of Adherent Cells for High-Throughput Flow Cytometry in 384-Well Microplate Format for Cell-Based Drug Library Screening
    Cornel, Annelisa M.
    Szanto, Celina L.
    van Til, Niek P.
    van Velzen, Jeroen F.
    Boelens, Jaap J.
    Nierkens, Stefan
    CYTOMETRY PART A, 2020, 97 (08) : 845 - 851
  • [24] Application of high-throughput affinity-selection mass spectrometry for screening of chemical compound libraries in lead discovery
    Zehender, Hartmut
    Mayr, Lorenz M.
    EXPERT OPINION ON DRUG DISCOVERY, 2007, 2 (02) : 285 - 294
  • [25] Development of resazurin-based assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei rhodesiense strain STIB 900 for the identification of potential anti-trypanosomal agents
    Lim, Kah Tee
    Zahari, Zuriati
    Amanah, Azimah
    Zainuddin, Zafarina
    Adenan, Mohd Ilham
    EXPERIMENTAL PARASITOLOGY, 2016, 162 : 49 - 56
  • [26] Kinase drug discovery by affinity selection/mass spectrometry (ASMS): Application to DNA damage checkpoint kinase Chk1
    Comess, Kenneth M.
    Trumbull, Jonathan D.
    Park, Chang
    Chen, Zehan
    Judge, Russell A.
    Voorbach, Martin J.
    Coen, Michael
    Gao, Lan
    Tang, Hua
    Kovar, Peter
    Cheng, Xueheng
    Schurdak, Mark E.
    Zhang, Haiying
    Sowin, Tom
    Burns, David J.
    JOURNAL OF BIOMOLECULAR SCREENING, 2006, 11 (07) : 755 - 764
  • [27] An affinity selection-mass spectrometry method for the identification of small molecule ligands from self-encoded combinatorial libraries -: Discovery of a novel antagonist of E-coli dihydrofolate reductase
    Annis, DA
    Athanasopoulos, J
    Curran, PJ
    Felsch, JS
    Kalghatgi, K
    Lee, WH
    Nash, HM
    Orminati, JPA
    Rosner, KE
    Shipps, GW
    Thaddupathy, GRA
    Tyler, AN
    Vilenchik, L
    Wagner, CR
    Wintner, EA
    INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2004, 238 (02) : 77 - 83
  • [28] RNA as a small molecule drug target: Discovery of selective RNA-binding small molecules by high-throughput affinity-selection mass spectrometry
    Rizvi, Noreen
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
  • [29] Pharmacokinetic screening for the selection of new drug discovery candidates is greatly enhanced through the use of liquid chromatography atmospheric pressure ionization tandem mass spectrometry
    Bryant, MS
    Korfmacher, WA
    Wang, SY
    Nardo, C
    Nomeir, AA
    Lin, CC
    JOURNAL OF CHROMATOGRAPHY A, 1997, 777 (01) : 61 - 66
  • [30] Rapid pharmacokinetic screening for the selection of new drug discovery candidates using a generic isocratic liquid chromatography-atomospheric pressure ionization tandem mass spectrometry method
    Colwell, LF
    Tamvakopoulos, CS
    Wang, PR
    Pivnichny, JV
    Shih, TL
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2002, 772 (01): : 89 - 98