Practical Aspects of Allogeneic Hematopoietic Cell Transplantation for Patients with Poor-Risk Chronic Lymphocytic Leukemia

被引：1
|
作者：
Delgado, Julio [1 ]
Duarte, Rafael F. [2 ]
机构：
[1] Hosp Santa Creu & Sant Pau, Dept Hematol, Barcelona, Spain
[2] ICO Hosp Duran & Reynals, Dept Hematol, Barcelona, Spain
来源：
THESCIENTIFICWORLDJOURNAL | 2011年 / 11卷
关键词：
chronic lymphocytic leukemia; allogeneic hematopoietic cell transplantation; MINIMAL RESIDUAL DISEASE; CONDITIONING REGIMENS; ALEMTUZUMAB; FLUDARABINE; LYMPHOMA; RITUXIMAB; THERAPY; SIROLIMUS; SURVIVAL; BLOOD;
D O I：
10.1100/tsw.2011.21
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Allogeneic hematopoietic cell transplantation has become a viable option for younger patients with poor-risk chronic lymphocytic leukemia. The results obtained with either conventional or reduced-intensity conditioning regimens have been recently evaluated and compared with alternative nontransplant strategies. This manuscript deals with practical aspects of the procedure, including patient and donor selection, conditioning regimen, GVHD prophylaxis, disease monitoring, infectious and noninfectious complications, and timing of the procedure. Finally, we speculate on how we could improve the results obtained with the procedure and new advances currently in clinical trials.
引用
收藏
页码：161 / 172
页数：12
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