Controversies in Pathology in Early-Stage Breast Cancer

被引:6
|
作者
Goldstein, S. Neal [1 ]
机构
[1] Adv Diagnost Lab, Redford, MI 48240 USA
关键词
CARCINOMA IN-SITU; LUMPECTOMY MARGIN ASSESSMENT; ATYPICAL DUCTAL HYPERPLASIA; POSITIVE SURGICAL MARGINS; TERM-FOLLOW-UP; CONSERVING THERAPY; LOCAL RECURRENCE; LOCOREGIONAL RECURRENCE; CONSERVATIVE SURGERY; RADIATION-THERAPY;
D O I
10.1016/j.semradonc.2010.08.003
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Breast-conserving therapy is a reliable, evidenced-based approach for early-stage breast carcinoma. This article reviews the issues and limitations related to simple margin measurements, data supporting the association between the amount of carcinoma near the margin, and ipsilateral breast failure risk. Additional factors pertinent to radiation oncologists include extensive intraductal carcinoma, lymphovascular space invasion, atypical ductal hyperplasia, and molecular clonality of ipsilateral breast failures as they relate to outcome. Semin Radiat Oncol 21:20-25 (C) 2011 Published by Elsevier Inc.
引用
收藏
页码:20 / 25
页数:6
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