Detection of Neurons on Images of the Histological Slices Using Convolutional Neural Network

被引:0
|
作者
Fomin, Ivan [1 ]
Mikhailov, Viktor [1 ]
Bakhshiev, Aleksandr [1 ]
Merkulyeva, Natalia [2 ,3 ]
Veshchitskii, Aleksandr [3 ]
Musienko, Pavel [2 ,4 ,5 ]
机构
[1] Russian State Sci Ctr Robot & Tech Cybernet, Tikhoretsky Prospect 21, St Petersburg 194064, Russia
[2] St Petersburg State Univ, Inst Translat Biomed, St Petersburg 194064, Russia
[3] RAS, Pavlov Inst Physiol, St Petersburg, Russia
[4] St Petersburg State Univ Aerosp Instrumentat, 67 B Morskaia St, St Petersburg 190000, Russia
[5] Childrens Surg & Orthoped Clin, Dept Nonpulm TB, Inst Phthysiopulmonol, St Petersburg, Russia
基金
俄罗斯科学基金会;
关键词
Neuron detection; Deep learning; Object detection; Image segmentation; Neural networks; Spinal cord slices; NeuN;
D O I
10.1007/978-3-319-66604-4_13
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
An automatic analysis of images of the histological slices is one of main steps in process of description of structure of neural network in norm and pathology. Understanding of structure and functions of that networks may help to improve neuro-rehabilitation technologies and to translate experimental data to the clinical practice. Main problem of the automatic analysis is complexity of research object and high variance of its parameters, such as thickness and transparency of slice, intensity and type of histological marker, etc. Variance of parameters make every step of neuron detection very hard and complex task. We represent algorithm of neuron detection on images of spinal cord slices using deep neural network. Networks with different parameters are compared to previous algorithm that based on pixels' filtration by color.
引用
收藏
页码:85 / 90
页数:6
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