Recombinant food allergens

被引：29
|
作者：
Lorenz, AR [1 ]
Scheurer, S [1 ]
Haustein, D [1 ]
Vieths, S [1 ]
机构：
[1] Paul Ehrlich Inst, Dept Allergol, D-63225 Langen, Germany
来源：
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2001年 / 756卷 / 1-2期
关键词：
reviews; food allergy; recombinant food allergen;
D O I：
10.1016/S0378-4347(01)00086-X
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Allergenic (glyco)proteins are the elicitors of food allergies and can cause acute severe hypersensitivity reactions. Recombinant food allergens are available in standardised quantity and constant quality. Therefore, they offer new perspectives to overcome current difficulties in the diagnosis, treatment and investigation of food allergies. This review summarises the expression strategies and characteristics of more than 40 recombinant food allergens that have been produced until today. Their IgE-binding properties are compared to those of their natural counterparts, in addition their application as diagnostic tools, the generation of hypoallergenic recombinant isoforms and mutants for therapeutic purposes, the determination of epitopes and cross-reactive structures are described. (C) 2001 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：255 / 279
页数：25
相关论文
共 50 条
  • [1] Recombinant antibodies for sensitive detection of food allergens
    Haka, J.
    Iljin, K.
    Niemi, M. H.
    Reddy, V. S.
    Takkinen, K.
    Laukkanen, M-L
    [J]. ALLERGY, 2015, 70 : 518 - 518
  • [2] Improvement of the diagnosis of food allergy with recombinant allergens
    Morisset, M.
    Codreanu, F.
    Astier, C.
    Olivier, R.
    Jacquenet, S.
    Bihain, B.
    Moneret-Vautrin, D. -A.
    Kanny, G.
    [J]. REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE, 2008, 48 (03): : 242 - 245
  • [3] Recombinant allergens in the diagnosis of food allergy: Which are the advantages?
    Ballmer-Weber, B. K.
    Lidholm, J.
    Vieths, S.
    [J]. REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE, 2007, 47 (03): : 126 - 128
  • [4] Improving diagnostic tests for food allergy with recombinant allergens
    Bohle, B
    Vieths, S
    [J]. METHODS, 2004, 32 (03) : 292 - 299
  • [5] Recombinant allergens
    Christophe Grégoire
    Martin D. Chapman
    [J]. Clinical Reviews in Allergy & Immunology, 2001, 21 : 215 - 227
  • [6] Recombinant allergens
    Grégoire, C
    Chapman, MD
    [J]. CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2001, 21 (2-3) : 215 - 227
  • [7] RECOMBINANT ALLERGENS AND ALLERGENS STANDARDIZATION - REPLY
    CHAPMAN, MD
    PLATTSMILLS, TAE
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 1992, 89 (04) : 922 - 922
  • [8] Recombinant allergens and immunotherapy
    Pauli, G.
    [J]. REVUE FRANCAISE D ALLERGOLOGIE ET D IMMUNOLOGIE CLINIQUE, 2007, 47 (03): : 133 - 138
  • [9] Recombinant allergens for immunotherapy
    Valenta, Rudolf
    Niederberger, Verena
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (04) : 826 - 830
  • [10] Recombinant allergens for immunotherapy
    Chapman, MD
    Smith, AM
    Vailes, LD
    Pomés, A
    [J]. ALLERGY AND ASTHMA PROCEEDINGS, 2002, 23 (01) : 5 - 8
12345