In this report, the recent and significant advances in headspace gas chromatography (HS-GC) and their resulting applications in the past five years (2002 to present) are reviewed and discussed. The discussion includes a brief overview of the recent advances in HS-GC techniques and theory, followed by examples of new applications and instrumentation for the various headspace analysis techniques. The techniques reviewed and discussed in this report include: static headspace, dynamic headspace, headspace solid phase microextraction (HS-SPME), and headspace single drop microextraction (HS-SDME). Examples of applications in environmental, clinical, forensic, biological, food, flavor and pharmaceutical analysis are provided. This report clearly indicates that research in HS-GC is very active and growing, with new applications being reported regularly.