Optimization of fiber optic probe distance for biomedical spectroscopy

被引：0
|
作者：
Wang, Bowen [1 ]
Tang, Yan [2 ]
Zhang, Xiaolei [2 ]
Fan, Shuzhen [2 ]
机构：
[1] Hosp Shandong Univ, 91 Shanda Bei Rd, Jinan 250100, Peoples R China
[2] Shandong Univ, Sch Informat Sci & Engn, Jinan 250100, Peoples R China
来源：
OPTICS IN HEALTH CARE AND BIOMEDICAL OPTICS IV | 2010年 / 7845卷
关键词：
biomedical spectroscopy; fiber optic probes; probe distance; reflectance; fluorescence; Raman; COLLECTION EFFICIENCY; CANCER; TISSUE;
D O I：
10.1117/12.871675
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
We present a theoretical model to maximize the illumination and collection efficiency in designing fiber optic probes for biomedical spectroscopy measurement. This model is in general applicable to probes with single or multiple fibers. We investigated a number of probe configurations and find that contact measurement is very inefficient for multi-fiber probes. Contact measurement is a good choice for single-fiber probes, but for multi-fiber probes, there is an optimal probe distance. By carefully choosing the probe and sample distance, the signal can be enhanced by 5-10 fold. Experiments demonstrate the distance dependence of collection efficiency in multi-fiber probes.
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页数：7
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