Exosome-driven lipolysis and bone marrow niche remodeling support leukemia expansion

被引:12
|
作者
Kumar, Bijender [2 ,4 ]
Orellana, Marvin [1 ]
Brooks, Jamison [1 ]
Madabushi, Srideshikan Sargur [1 ]
Vishwasrao, Paresh [1 ]
Parra, Liliana E. [1 ]
Sanchez, James [3 ]
Salhotra, Amandeep [2 ,3 ]
Stein, Anthony [2 ,3 ]
Chen, Ching-Cheng [2 ]
Marcucci, Guido [2 ,3 ]
Hui, Susanta Kumar [1 ]
机构
[1] City Hope Natl Med Ctr, Beckman Res Inst, Dept Radiat Oncol, 1500 E Duarte Rd, Duarte, CA 91010 USA
[2] City Hope Natl Med Ctr, Stem Cell Transplantat Inst, Hematol Malignancies, 1500 E Duarte Rd, Duarte, CA 91010 USA
[3] City Hope Natl Med Ctr, Dept Hematol & HCT, 1500 E Duarte Rd, Duarte, CA 91010 USA
[4] Univ Texas MD Anderson Canc Ctr, Dept Stem Cell Transplantat & Cellular Therapy, Houston, TX 77030 USA
关键词
STEM-CELLS;
D O I
10.3324/haematol.2019.246058
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1484 / 1488
页数:5
相关论文
共 50 条
  • [1] Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells
    Nikolina Dioufa
    Amanda M. Clark
    Bo Ma
    Colin H. Beckwitt
    Alan Wells
    Molecular Cancer, 16
  • [2] Bi-directional exosome-driven intercommunication between the hepatic niche and cancer cells
    Dioufa, Nikolina
    Clark, Amanda M.
    Ma, Bo
    Beckwitt, Colin H.
    Wells, Alan
    MOLECULAR CANCER, 2017, 16
  • [3] Bone marrow niche and leukemia
    Ho, A. D.
    Wagner, W.
    CANCER STEM CELLS: NOVEL CONCEPTS AND PROSPECTS FOR TUMOR THERAPY, 2007, 5 : 125 - +
  • [4] Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion
    B Kumar
    M Garcia
    L Weng
    X Jung
    J L Murakami
    X Hu
    T McDonald
    A Lin
    A R Kumar
    D L DiGiusto
    A S Stein
    V A Pullarkat
    S K Hui
    N Carlesso
    Y-H Kuo
    R Bhatia
    G Marcucci
    C-C Chen
    Leukemia, 2018, 32 : 575 - 587
  • [5] Acute myeloid leukemia transforms the bone marrow niche into a leukemia-permissive microenvironment through exosome secretion
    Kumar, B.
    Garcia, M.
    Weng, L.
    Jung, X.
    Murakami, J. L.
    Hu, X.
    McDonald, T.
    Lin, A.
    Kumar, A. R.
    DiGiusto, D. L.
    Stein, A. S.
    Pullarkat, V. A.
    Hui, S. K.
    Carlesso, N.
    Kuo, Y-H
    Bhatia, R.
    Marcucci, G.
    Chen, C-C
    LEUKEMIA, 2018, 32 (03) : 575 - 587
  • [6] Bone marrow neoplastic niche in leukemia
    Azizidoost, Shirin
    Babashah, Sadegh
    Rahim, Fakher
    Shahjahani, Mohammad
    Saki, Najmaldin
    HEMATOLOGY, 2014, 19 (04) : 232 - 238
  • [7] Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits
    Li, Ziru
    Bowers, Emily
    Zhu, Junxiong
    Yu, Hui
    Hardij, Julie
    Bagchi, Devika P.
    Mori, Hiroyuki
    Lewis, Kenneth T.
    Granger, Katrina
    Schill, Rebecca L.
    Romanelli, Steven M.
    Abrishami, Simin
    Hankenson, Kurt D.
    Singer, Kanakadurga
    Rosen, Clifford J.
    MacDougald, Ormond A.
    ELIFE, 2022, 11
  • [8] Acute myeloid leukemia-induced remodeling of the human bone marrow niche predicts clinical outcome
    Chen, Yiyang
    Hoffmeister, Lina Marie
    Zaun, Yasmin
    Arnold, Lucas
    Schmid, Kurt Werner
    Giebel, Bernd
    Klein-Hitpass, Ludger
    Hanenberg, Helmut
    Squire, Anthony
    Reinhardt, H. Christian
    Duehrsen, Ulrich
    Bertram, Stefanie
    Hanoun, Maher
    BLOOD ADVANCES, 2020, 4 (20) : 5257 - 5268
  • [9] IFNα-mediated remodeling of endothelial cells in the bone marrow niche
    Prendergast, Aine M.
    Kuck, Andrea
    van Essen, Mieke
    Haas, Simon
    Blaszkiewicz, Sandra
    Essers, Marieke A. G.
    HAEMATOLOGICA, 2017, 102 (03) : 445 - 453
  • [10] Bone marrow adipocytes resist lipolysis and remodeling in response to β-adrenergic stimulation
    Scheller, Erica L.
    Khandaker, Shaima
    Learman, Brian S.
    Cawthorn, William P.
    Anderson, Lindsay M.
    Pham, H. A.
    Robles, Hero
    Wang, Zhaohua
    Li, Ziru
    Parlee, Sebastian D.
    Simon, Becky R.
    Mori, Hiroyuki
    Bree, Adam J.
    Craft, Clarissa S.
    MacDougald, Ormond A.
    BONE, 2019, 118 : 32 - 41