Characterizing a Clinical Trial - Representative, Real-World Population with Heart Failure with Reduced Ejection Fraction

被引：1

作者：

Wells, Quinn S. ^{[1
,2
]}

Farber-Eger, Eric ^{[1
,2
]}

Lipworth, Loren ^{[2
,3
]}

Dluzniewski, Paul ^{[4
]}

Dent, Ricardo ^{[4
]}

Umeijiego, John ^{[4
]}

Cohen, Sarah S. ^{[3
,5
]}

机构：

[1] Vanderbilt Univ, Dept Med, Div Cardiovasc Med, Med Ctr, Nashville, TN USA

[2] Vanderbilt Univ, Med Ctr, Vanderbilt Translat & Clin Cardiovasc Res Ctr VTR, Nashville, TN USA

[3] Vanderbilt Univ, Dept Med, Div Epidemiol, Med Ctr, Nashville, TN 37235 USA

[4] Amgen Inc, Ctr Observat Res, Thousand Oaks, CA 91320 USA

[5] Toxstrategies Inc, Epidstrategies, Cary, NC 27511 USA

来源：

CLINICAL EPIDEMIOLOGY | 2022年 / 14卷

关键词：

heart failure; reduced ejection fraction; real-world evidence; electronic health record; RANDOMIZED INTERVENTION TRIAL; CIBIS-II; MORTALITY; ENALAPRIL; SURVIVAL; METOPROLOL; MORBIDITY; OUTCOMES;

D O I：

10.2147/CLEP.S341919

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

li li li Conclusion: Approximately 40% of RW HFrEF patients met criteria for the GALACTICHF trial. While findings of ongoing clinical trials may be directly generalizable to this sizable proportion of patients, future trials should examine whether the majority of patients with lower prevalence of comorbidities and rate of HF hospitalization could benefit from emerging HF treatments.

引用

页码：39 / 49

页数：11

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