Chronic medication intake in patients with stable coronary heart disease across Europe: Evidence from the daily clinical practice. Results from the ESC EORP European Survey of Cardiovascular Disease Prevention and Diabetes (EUROASPIRE IV) Registry

被引:9
|
作者
De Smedt, Delphine [1 ]
De Backer, Tine [2 ,3 ]
Petrovic, Mirko [2 ,3 ]
De Backer, Guy [1 ]
Wood, David [4 ,5 ]
Kotseva, Kornelia [5 ,6 ]
De Bacquer, Dirk [1 ]
机构
[1] Univ Ghent, Dept Publ Hlth & Primary Care, Ghent, Belgium
[2] Univ Ghent, Dept Internal Med & Pediat, Ghent, Belgium
[3] Ghent Univ Hosp, Ghent, Belgium
[4] Imperial Coll London, Natl Heart & Lung Inst, London, England
[5] Natl Univ Ireland, Natl Inst Prevent & Cardiovasc Hlth, Galway, Ireland
[6] Imperial Coll Healthcare NHS Trust, London, England
关键词
Coronary heart disease; EUROASPIRE; Medication; SECONDARY PREVENTION; DRUGS;
D O I
10.1016/j.ijcard.2019.09.015
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: As advised by the European guidelines on cardiovascular prevention, medication intake is a major component of secondary prevention. The aim of this study is to provide an in-depth overview of the medication intake in stable European coronary heart disease (CHD) patients. Methods: Analyses are based on the EUROASPIRE IV survey, including CHD patients (18 to 80 years) who were hospitalized for a coronary event. These patients were interviewed and examined 6 months to 3 years after their hospitalization. Information on cardiovascular medication intake is available for 7953 patients. Results: About 99.2% of patients were on any kind of cardiovascular medication and 67.6% of patients were taking at least 5 different cardiovascular drugs. Overall, even when patients are taking the recommended drug combination as advised by the European guidelines - accounting for their disease profile - a large proportion of patients is still not on blood pressure, LDL-C or HbA1c target In addition, huge variations were seen in medication dose intake across countries. Comparing the dose intake to the defined daily dose (DDD as published by the WHO) indicated a substantial deviation from the DDDs for a large proportion of patients. Conclusion: This study provides a unique overview of the cardiovascular medication intake in CHD patients. Overall, even when patients are taking the advised drug combination, a large proportion of patients is still not on risk factor target. Physicians should seek for a balance in medication intake and appropriate dose, accounting both for the benefits and risks of chronic drug intake. (C) 2019 Elsevier B.V. All rights reserved.
引用
收藏
页码:7 / 13
页数:7
相关论文
共 42 条
  • [1] EQ-5D in coronary patients: what are they suffering from? Results from the ESC EORP European Survey of Cardiovascular Disease Prevention and Diabetes (EUROASPIRE IV) Registry
    Delphine De Smedt
    Kornelia Kotseva
    Guy De Backer
    David Wood
    Lisa Van Wilder
    Dirk De Bacquer
    [J]. Quality of Life Research, 2020, 29 : 1037 - 1046
  • [2] EQ-5D in coronary patients: what are they suffering from? Results from the ESC EORP European Survey of Cardiovascular Disease Prevention and Diabetes (EUROASPIRE IV) Registry
    De Smedt, Delphine
    Kotseva, Kornelia
    De Backer, Guy
    Wood, David
    Van Wilder, Lisa
    De Bacquer, Dirk
    [J]. QUALITY OF LIFE RESEARCH, 2020, 29 (04) : 1037 - 1046
  • [3] Management of overweight and obesity in patients with coronary heart disease across Europe: results from EUROASPIRE IV survey
    Kotseva, K.
    De Bacquer, D.
    Jennings, C.
    Wood, D.
    [J]. EUROPEAN HEART JOURNAL, 2015, 36 : 1149 - 1149
  • [4] Management of dyslipidaemia in patients with coronary heart disease: Results from the ESC-EORP EUROASPIRE V survey in 27 countries
    De Backer, Guy
    Jankowski, Piotr
    Kotseva, Kornelia
    Mirrakhimov, Erkin
    Reiner, Zeljko
    Ryden, Lars
    Tokgozoglu, Lale
    Wood, David
    De Bacquer, Dirk
    Abreu, A.
    Aguiar, C.
    Badariene, J.
    Bruthans, J.
    Castro Conde, A.
    Cifkova, R.
    Crowley, J.
    Davletov, K.
    De Smedt, D.
    De Sutter, J.
    Deckers, J. W.
    Dilic, M.
    Dolzhenko, M.
    Druais, H.
    Dzerve, V.
    Erglis, A.
    Fras, Z.
    Gaita, D.
    Gotcheva, N.
    Grobbee, D. E.
    Gyberg, V.
    Ali, H. Hasan
    Heuschmann, P.
    Hoes, A. W.
    Lalic, N.
    Lehto, S.
    Lovic, D.
    Maggioni, A. P.
    Mancas, S.
    Marques-Vidal, P.
    Mellbin, L.
    Milicic, D.
    Oganov, R.
    Pogosova, N.
    Stagmo, M.
    Stoerk, S.
    Sundvall, J.
    Tsioufis, K.
    Vulic, D.
    Wood, D. A.
    Jennings, C.
    [J]. ATHEROSCLEROSIS, 2019, 285 : 135 - 146
  • [5] Smoking cessation in European patients with coronary heart disease. Results from the EUROASPIRE IV survey: A registry from the European Society of Cardiology
    Snaterse, M.
    Deckers, J. W.
    Lenzen, M. J.
    Jorstad, H. T.
    De Bacquer, D.
    Peters, R. J. G.
    Jennings, C.
    Kotseva, K.
    op Reimer, W. J. M. Scholte
    [J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 2018, 258 : 1 - 6
  • [6] Assessing the probability of risk factor control in patients with coronary heart disease: results from the ESC-EORP EUROASPIRE V survey
    Moerschel, Katharina Selda
    De Bacquer, Dirk
    De Backer, Guy
    Wood, David
    Kotseva, Kornelia
    Wellmann, Juergen
    Prugger, Christof
    [J]. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, 2022, 29 (10) : 1465 - 1475
  • [7] Alcohol consumption patterns across Europe and adherence to the European guidelines in coronary patients: findings from the ESC-EORP EUROASPIRE V survey
    Van De Luitgaarden, I
    Schrieks, I
    De Bacquer, D.
    Van Oort, S.
    Mirrakhimov, E.
    Pogosova, N.
    Davletov, K.
    Dolzhenko, M.
    Van Ballegooijen, A.
    Kolseva, K.
    Grobbee, D.
    Beulens, J.
    [J]. EUROPEAN HEART JOURNAL, 2020, 41 : 2823 - 2823
  • [8] Readiness for smoking cessation in coronary heart disease patients across Europe: Results from the EUROASPIRE III survey
    Prugger, Christof
    Wellmann, Juergen
    Heidrich, Jan
    De Bacquer, Dirk
    De Backer, Guy
    Perier, Marie-Cecile
    Empana, Jean-Philippe
    Reiner, Zeljko
    Fras, Zlatko
    Jennings, Catriona
    Kotseva, Kornelia
    Wood, David
    Keil, Ulrich
    [J]. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY, 2015, 22 (09) : 1212 - 1219
  • [9] Alcohol consumption patterns across Europe and adherence to the European guidelines in coronary patients: Findings from the ESC-EORP EUROASPIRE V survey
    van de Luitgaarden, Inge A. T.
    Schrieks, Ilse C.
    De Bacquer, Dirk
    van Oort, Sabine
    Mirrakhimov, Erkin M.
    Pogosova, Nana
    Davletov, Kairat
    Dolzhenko, Maryna
    van Ballegooijen, Adriana J.
    Kotseva, Kornelia
    Grobbee, Diederick E.
    Beulens, Joline W. J.
    [J]. ATHEROSCLEROSIS, 2020, 313 : 35 - 42
  • [10] Cost-effectiveness of optimized adherence to prevention guidelines in European patients with coronary heart disease: Results from the EUROASPIRE IV survey
    De Smedt, Delphine
    Annemans, Lieven
    De Backer, Guy
    Kotseva, Kornelia
    Ryden, Lars
    Wood, David
    Amouyel, Philippe
    Bruthans, Jan
    Cifkova, Renata
    De Sutter, Johan
    Dolzhenko, Marina
    Erglis, Andrejs
    Gotcheva, Nina
    Gyberg, Viveca
    Laucevicius, Aleksandras
    Lovic, Dragan
    Oganov, Rafael
    Pajak, Andrzej
    Pogosova, Nana
    Reiner, Zeljko
    Stagmo, Martin
    De Bacquer, Dirk
    [J]. INTERNATIONAL JOURNAL OF CARDIOLOGY, 2018, 272 : 20 - 25