PHARMACOKINETICS, SAFETY, AND TOLERABILITY OF PSI-352938, A NOVEL NUCLEOTIDE POLYMERASE INHIBITOR FOR HCV, FOLLOWING SINGLE ASCENDING ORAL DOSES IN HEALTHY SUBJECTS

被引：0
|
作者：
Symonds, William [1 ]
Denning, Jill M. [1 ]
Albanis, Efsevia [1 ]
Wright, Robert [2 ]
Lai, Alexander [2 ]
Berrey, Michelle [1 ]
机构：
[1] Pharmasset Inc, Princeton, NJ USA
[2] Covance Clin Res Unit Inc, Madison, WI USA
来源：
HEPATOLOGY | 2010年 / 52卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
1890
引用
收藏
页码：1219A / 1219A
页数：1
相关论文
共 50 条
  • [31] Pharmacokinetics, safety, and tolerability of the novel oral direct renin inhibitor aliskiren in elderly healthy subjects
    Vaidyanathan, Sujata
    Reynolds, Christine
    Yeh, Ching-Ming
    Bizot, Marie-Noelle
    Dieterich, Hans Armin
    Howard, Dan
    Dole, William P.
    JOURNAL OF CLINICAL PHARMACOLOGY, 2007, 47 (04): : 453 - 460
  • [32] Safety and Pharmacokinetics of Single and Multiple Oral Doses of MK-8742, an HCV NS5A Inhibitor, in Healthy Subjects
    Mangin, Eric
    Yeh, Wendy W.
    Caro, Luzelena
    Lipardi, Concetta
    Mitselos, Anna
    Fraser, Iain P.
    Jumes, Patricia
    Huang, Xiaobi
    Dreyer, Daniel
    Van Bortel, Lucas M.
    Butterton, Joan R.
    HEPATOLOGY, 2013, 58 : 444A - 444A
  • [33] First-time-in-man, safety/tolerability and pharmacokinetics of ascending oral doses of apremilast (APR) in healthy subjects (HS)
    Wu, A.
    Scheffler, M.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2011, 131 : S86 - S86
  • [34] Tolerability and pharmacokinetics of BILN 2061, a novel HCV serine protease inhibitor, after oral single doses of 5 to 2400 mg in healthy male subjects.
    Narjes, H
    Yong, CL
    Stähle, H
    Steinmann, G
    HEPATOLOGY, 2002, 36 (04) : 363A - 363A
  • [35] Safety and Tolerability of Single Ascending Doses of DRL-17822, a Potent CETP Inhibitor, in Healthy Male Subjects
    Bapat, Abhijit
    Rao, Mallikarjuna
    Vittal, Shivva
    Mangapathiraju, Tippana
    Hasham, Sumera
    Sai, Sesha
    Alikunju, Shanavas
    Sadashivam, Vasu
    Allenby, Kent
    Kumar, Rajinder
    DIABETES, 2010, 59 : A194 - A195
  • [36] Safety, tolerability, and pharmacokinetics of single ascending doses of synthetic genistein (Bonistein™) in healthy volunteers
    Ullmann, U
    Metzner, J
    Frank, T
    Cohn, W
    Riegger, C
    ADVANCES IN THERAPY, 2005, 22 (01) : 65 - 78
  • [37] Safety, tolerability, and pharmacokinetics of single ascending doses of synthetic genistein (Bonistein™) in healthy volunteers
    Uwe Ullmann
    Juergen Metzner
    Thomas Frank
    William Cohn
    Christoph Riegger
    Advances in Therapy, 2005, 22 : 65 - 78
  • [38] Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Sotagliflozin After Multiple Ascending Doses in Chinese Healthy Subjects
    He, Xuemei
    Gao, Xin
    Xie, Panpan
    Liu, Yuan
    Bai, Wenjing
    Liu, Yue
    Shi, Aixin
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2022, 16 : 2967 - 2980
  • [39] Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses of TAK-935 in Healthy Subjects
    Wang, Shining
    Chen, Grace
    Uz, Tolga
    Affinito, John
    NEUROLOGY, 2018, 90
  • [40] Tolerability and pharmacokinetics of ebrotidine in healthy subjects given single and repeated oral doses
    Farre, M
    Roset, PN
    Badenas, JM
    Ugena, B
    Marquez, M
    Albet, C
    Herrero, E
    Ortiz, JA
    ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, 1997, 47-1 (4A): : 528 - 530
12345