Layer-by-layer assembly methods and their biomedical applications

被引:32
|
作者
Zhang, Zhuying [1 ]
Zeng, Jinfeng [1 ,2 ]
Groll, Jurgen [3 ,4 ]
Matsusaki, Michiya [1 ,5 ]
机构
[1] Osaka Univ, Grad Sch Engn, Dept Appl Chem, 2-1 Yamadaoka, Suita, Osaka 5650871, Japan
[2] Japan Soc Promot Sci, Chiyoda Ku, Kojimachi Business Ctr Bldg,5-3-1 Kojimachi, Tokyo 1020083, Japan
[3] Univ Wurzburg, Dept Funct Mat Med & Dent, Inst Funct Mat & Biofabricat IFB, Pleicherwall 2, D-97070 Wurzburg, Germany
[4] Univ Wurzburg, Bavarian Polymer Inst BPI, Pleicherwall 2, D-97070 Wurzburg, Germany
[5] Osaka Univ, Grad Sch Engn, Joint Res Lab TOPPAN Adv Cell Regulatory Chem, 2-1 Yamadaoka, Suita, Osaka 5650871, Japan
关键词
MULTILAYER COATINGS; POLY(ACRYLIC ACID); CONTROLLED-RELEASE; POLYSACCHARIDE NANOSHEET; POLYELECTROLYTE CHAINS; HYALURONIC-ACID; CELL; FILMS; TISSUE; DEPOSITION;
D O I
10.1039/d2bm00497f
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Layer-by-layer (LbL) assembly has attracted much interest because of its ability to provide nanoscale control over film characteristics and because of a wide choice of available materials. The methods of LbL not only determine the process properties, but also directly affect film properties. In this review, we will discuss LbL methodologies that have been used in biomedical fields. Special attention is devoted to different properties arising from methods that allow for diverse biomedical applications, ranging from surface modification to tissue engineering. We conclude with a discussion of the current challenges and future perspectives.
引用
收藏
页码:4077 / 4094
页数:18
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