Clinicopathological and molecular characteristics, treatment patterns, and outcomes in patients with KRAS p.G12C-mutated metastatic non-small cell lung cancer (NSCLC) in the AACR Project GENIE database.

被引:0
|
作者
Ricciuti, Biagio [1 ]
Wang, Chenguang [2 ]
Rizvi, Hira [3 ]
Egger, Jacklynn [1 ]
LeNoue-Newton, Michele [4 ]
Holt, Marilyn [4 ]
Aggarwal, Shivani
Tu, Huakang [5 ]
Hsu, Hil [5 ]
Wang, Xuena [5 ]
Ngarmchamnanrith, Gataree [5 ]
Chia, Victoria [5 ]
Lee, Jocelyn [6 ]
Scharpf, Robert [2 ]
Anagnostou, Valsamo [2 ]
Lovly, Christine [4 ]
Riely, Greg [3 ]
Awad, Mark [1 ]
机构
[1] Dana Farber Canc Inst, Boston, MA 02115 USA
[2] Johns Hopkins Med Inst, Baltimore, MD 21205 USA
[3] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
[4] Vanderbilt Ingram Canc Ctr, Nashville, TN USA
[5] Amgen Inc, Thousand Oaks, CA 91320 USA
[6] Amer Assoc Canc Res, Philadelphia, PA USA
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
102
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Molecular and clinical characteristics of patients with non-small-cell lung cancer (NSCLC) harboring KRAS G12V mutations
    John, Felix
    Ruge, Lea
    Scharpenseel, Heather
    Siemanowski, Janna
    Fassunke, Jana
    Riedel, Richard
    Michels, Sebastian Yves Friedrich
    Fischer, Rieke Nila
    Rasokat, Anna
    Schulte, Wolfgang
    Franke, Karl-Josef
    Graeven, Ullrich
    Kappes, Jutta
    Kron, Anna
    Siebolts, Udo
    Merkelbach-Bruse, Sabine
    Buettner, Reinhard
    Wolf, Juergen
    Scheffler, Matthias
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [42] Understanding Treatment Preferences of Patients With KRAS p.G12C[LC1] [MK2] - Mutated Advanced Non-Small Cell Lung Cancer
    Myers, K.
    Barrett, A.
    Leach, C.
    Matsuda, T.
    Stevinson, K.
    Lu, C.
    Fu, C.
    Bittoni, M.
    Presley, C.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (10) : S1121 - S1122
  • [43] Real-World outcomes of Non-Small cell lung cancer patients harbouring KRAS G12C and KRAS G12D mutations
    Shahnam, Adel
    Davis, Alexander
    Brown, Lauren Julia
    Sullivan, Isaac
    Lin, Kevin
    Ng, Chien
    Yeo, Nicholas
    Kong, Benjamin Y.
    Khoo, Trisha
    Warburton, Lydia
    Da Silva, Ines Pires
    Mullally, William
    Xu, Wen
    O'Byrne, Ken
    Bray, Victoria
    Pal, Abhijit
    Mersaides, Antony
    Itchins, Malinda
    Arulananda, Surein
    Nagrial, Adnan
    Kao, Steven
    Alexander, Marliese
    Lee, Chee Khoon
    Solomon, Benjamin
    John, Thomas
    LUNG CANCER, 2025, 201
  • [44] Trimodality therapy in the treatment of stage IIIA non-small cell lung cancer (NSCLC): Analysis of the National Cancer Database.
    Behera, Madhusmita
    Steuer, Conor Ernst
    Fernandez, Felix
    Liu, Yuan
    Fu, Chao
    Gillespie, Theresa Wicklin
    Higgins, Kristin Ann
    Saba, Nabil F.
    Pillai, Rathi Narayana
    Force, Seth
    Pakkala, Suchita
    Shin, Dong Moon
    Owonikoko, Taofeek Kunle
    Belani, Chandra Prakash
    Curran, Walter J.
    Khuri, Fadlo Raja
    Ramalingam, Suresh S.
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [45] Sotorasib versus Docetaxel for treatment of US and Chinese patients with advanced non-small-cell lung cancer with KRAS p.G12C-mutated: A cost-effectiveness analysis to inform drug pricing
    Jiang, Yunlin
    Zhao, Mingye
    Liu, Ruolin
    Zheng, Xueping
    MEDICINE, 2023, 102 (50) : E36387
  • [46] Resistance to KRAS G12C Inhibition in Non-small Cell Lung Cancer
    Alessandro Di Federico
    Ilaria Ricciotti
    Valentina Favorito
    Sandra Vietti Michelina
    Pietro Scaparone
    Giulio Metro
    Andrea De Giglio
    Federica Pecci
    Giuseppe Lamberti
    Chiara Ambrogio
    Biagio Ricciuti
    Current Oncology Reports, 2023, 25 : 1017 - 1029
  • [47] Resistance to KRAS G12C Inhibition in Non-small Cell Lung Cancer
    Di Federico, Alessandro
    Ricciotti, Ilaria
    Favorito, Valentina
    Michelina, Sandra Vietti
    Scaparone, Pietro
    Metro, Giulio
    De Giglio, Andrea
    Pecci, Federica
    Lamberti, Giuseppe
    Ambrogio, Chiara
    Ricciuti, Biagio
    CURRENT ONCOLOGY REPORTS, 2023, 25 (09) : 1017 - 1029
  • [48] Patient-reported outcomes (PRO) from the phase 2 CodeBreaK 100 trial evaluating sotorasib in KRAS p.G12C mutated non-small cell lung cancer (NSCLC).
    Spira, Alexander I.
    Wilson, Frederick Hugh
    Shapiro, Geoffrey
    Dooms, Christophe
    Curioni-Fontecedro, Alessandra
    Esaki, Taito
    Barlesi, Fabrice
    Cocks, Kim
    Trigg, Andrew
    Stevinson, Kendall
    Matsuda, Tara
    Tran, Qui
    Gray, Jhanelle Elaine
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [49] Clinicopathological characteristics and treatment patterns observed in real-world care in patients with advanced non-small cell lung cancer (NSCLC) and KRAS G12C mutations in the Flatiron Health (FH)-Foundation Medicine (FMI) Clinico-Genomic Database (CGDB)
    Aggarwal, S.
    Whipple, S.
    Hsu, H.
    Tu, H.
    Carrigan, G.
    Wang, X.
    Ngarmchamnanrith, G.
    Chia, V.
    ANNALS OF ONCOLOGY, 2020, 31 : S860 - S860
  • [50] Systemic Treatment Patterns and Outcomes in Patients With EGFR Mutated Non-small Cell Lung Cancer and Leptomeningeal Disease
    Merkhofer, Cristina M.
    Eastman, Boryana
    Densmore, Isabella
    Halasz, Lia M.
    McGranahan, Tresa
    Baik, Christina
    CLINICAL LUNG CANCER, 2022, 23 (05) : 446 - 455