Pharmacological characterization of CHI25243, a novel potent inhaled inhibitor of neutrophil elastase

被引：0
|
作者：
Miglietta, Daniela
Carnini, Chiara
Puviani, Veronica
Finch, Harry
Fox, Craig
Fitzgerald, Mary
Patacchini, Riccardo
Civelli, Maurizio
Villetti, Gino
机构：
来源：
EUROPEAN RESPIRATORY JOURNAL | 2016年 / 48卷
关键词：
Anti-inflammatory; Inflammation; Infections;
D O I：
10.1183/13993003.congress-2016.OA4539
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
OA4539
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Chf6333: Pharmacological And Pharmacokinetic Characterization Of A Novel Potent Inhaled Inhibitor Of Neutrophil Elastase
    Carnini, C.
    Brogin, G.
    Patacchini, R.
    Miglietta, D.
    Stefani, M.
    Finch, H.
    Fitzgerald, M.
    Fox, C.
    Puccini, P.
    Villetti, G.
    Civelli, M.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2017, 195
  • [2] Pharmacological characterization of a novel orally active neutrophil elastase inhibitor
    Kuromiya, A
    Okazaki, H
    Tsuji, J
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 230 : U2691 - U2692
  • [3] BIOCHEMICAL AND PHARMACOLOGICAL CHARACTERIZATION OF ICI 186,756 - A NOVEL, POTENT, AND SELECTIVE INHIBITOR OF HUMAN NEUTROPHIL ELASTASE
    WILLIAMS, JC
    STEIN, RL
    STRIMPLER, AM
    REAVES, B
    KRELL, RD
    EXPERIMENTAL LUNG RESEARCH, 1991, 17 (04) : 725 - 741
  • [4] AZD9668: Pharmacological Characterization of a Novel Oral Inhibitor of Neutrophil Elastase
    Stevens, T.
    Ekholm, K.
    Granse, M.
    Lindahl, M.
    Kozma, V.
    Jungar, C.
    Ottosson, T.
    Falk-Hakansson, H.
    Churg, A.
    Wright, J. L.
    Lal, H.
    Sanfridson, A.
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2011, 339 (01): : 313 - 320
  • [5] Pharmacological characterization of AX-9657, a potent and selective neutrophil elastase inhibitor with good lung distribution
    Ishiyama, Junichi
    Araki, Kenji
    Miura, Masahiro
    Kitamura, Yoshiaki
    Izawa, Shigeru
    Okerberg, Eric S.
    Lin, Emme C. K.
    Shreder, Kevin R.
    Murakami, Koji
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 237
  • [6] Effect of POL6014, a Potent and Selective Inhaled Neutrophil Elastase Inhibitor, in a Rat Model of Lung Neutrophil Activation
    Kessler, O. Sellier
    Lemercier, G.
    Schmitt, M.
    Weinbrenner, S.
    Chevalier, E.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2018, 197
  • [7] Pharmacological activities of TEI-8362, a novel inhibitor of human neutrophil elastase
    Mitsuhashi, H
    Nonaka, T
    Hamamura, I
    Kishimoto, T
    Muratani, E
    Fujii, K
    BRITISH JOURNAL OF PHARMACOLOGY, 1999, 126 (05) : 1147 - 1152
  • [8] BIOCHEMICAL-CHARACTERIZATION OF ICI-200,880 - A NOVEL, POTENT AND SELECTIVE INHIBITOR OF HUMAN NEUTROPHIL ELASTASE
    KRELL, RD
    STEIN, RL
    STRIMPLER, AM
    TRAINOR, D
    EDWARDS, P
    WOLANIN, D
    WILDONGER, R
    SCHWARTZ, J
    HESP, B
    GILES, RE
    WILLIAMS, JC
    FASEB JOURNAL, 1988, 2 (04): : A346 - A346
  • [9] MOLECULAR CHARACTERIZATION OF MONOCYTE NEUTROPHIL EI, A NOVEL HUMAN ELASTASE INHIBITOR
    REMOLDODONNELL, E
    CHIN, J
    ALBERTS, M
    FASEB JOURNAL, 1992, 6 (05): : A1974 - A1974
  • [10] Biochemical and pharmacological characterization of FK706, a novel elastase inhibitor
    Shinguh, Y
    Imai, K
    Yamazaki, A
    Inamura, N
    Shima, I
    Wakabayashi, A
    Higashi, Y
    Ono, T
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1997, 337 (01) : 63 - 71
12345