A green route for the synthesis of pyrrolo[2,3-d]pyrimidine derivatives catalyzed by β-cyclodextrin

被引：12

作者：

Yadav, Vijay B. ^{[1
]}

Rai, Pragati ^{[1
]}

Sagir, Hozeyfa ^{[1
]}

Kumar, Akhilesh ^{[1
]}

Siddiqui, I. R. ^{[1
]}

机构：

[1] Univ Allahabad, Dept Chem, Lab Green Synth, Allahabad 211002, Uttar Pradesh, India

来源：

NEW JOURNAL OF CHEMISTRY | 2018年 / 42卷 / 01期

关键词：

NUCLEOSIDE ANTIBIOTICS; ANTIVIRAL ACTIVITY; ANALOGS; SANGIVAMYCIN; TOYOCAMYCIN; TOFACITINIB; INHIBITORS; PYRROLE; CANCER;

D O I：

10.1039/c7nj03577b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, we present the synthesis of pyrrolo[2,3-d]pyrimidine derivatives, which are important heterocyclic scaffolds in the field of synthetic and pharmaceutical research, via biomimetic catalysis. This strategy involves the use of beta-cyclodextrin as a reusable promoter and water as an eco-friendly reaction medium. The merits of this protocol are high atom economy, mild reaction conditions, good yields of desired products in short reaction times, and reusable reaction medium.

引用

页码：628 / 633

页数：6

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