Influenza induces GM-CSF deficiency: lung-specific overexpression after infection confers protection

被引:0
|
作者
Halstead, Eric [1 ]
Guo, Weichao [1 ]
Yang, Linlin [1 ]
Hu, Sanmei [3 ]
Umstead, Todd [1 ]
Hartshorn, Kevan [2 ]
White, Mitch [2 ]
Chroneos, Zissis [1 ]
机构
[1] Penn State Univ, Coll Med, Hershey, PA USA
[2] Boston Univ, Sch Med, Hematol & Med Oncol, Boston, MA 02118 USA
[3] Temple Univ, Clin Genet & Mol Biochem, Philadelphia, PA 19122 USA
来源
JOURNAL OF IMMUNOLOGY | 2015年 / 194卷
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
INC1P.355
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Deficiency of lung-specific claudin-18 leads to aggravated infection with Cryptococcus deneoformans through dysregulation of the microenvironment in lungs
    Ko Sato
    Ikumi Matsumoto
    Koya Suzuki
    Atsushi Tamura
    Aki Shiraishi
    Hiroshi Kiyonari
    Jun Kasamatsu
    Hideki Yamamoto
    Tomomitsu Miyasaka
    Daiki Tanno
    Anna Miyahara
    Tong Zong
    Takafumi Kagesawa
    Akiho Oniyama
    Kotone Kawamura
    Yuki Kitai
    Aya Umeki
    Emi Kanno
    Hiromasa Tanno
    Keiko Ishii
    Sachiko Tsukita
    Kazuyoshi Kawakami
    Scientific Reports, 11
  • [32] Failed Containment Of Fungal Lung Infection In Gm-Csf Deficient Mice Is Associated With Impaired Accumulation And Differentiation Of Alveolar And Exudate Macrophages
    Osterholzer, J. J.
    Chen, G. -H.
    Olszewski, M. A.
    Zhang, Y.
    Toews, G. B.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011, 183
  • [33] Combinatorial liposomal peptide vaccine induces IgA and confers protection against influenza virus and bacterial super-infection
    Zaman, Mehfuz
    Huber, Victor C.
    Heiden, Dustin L.
    DeHaan, Katerina N.
    Chandra, Sanyogita
    Erickson, Demi
    Ozberk, Victoria
    Pandey, Manisha
    Bailly, Benjamin
    Martin, Gael
    Langshaw, Emma L.
    Zaid, Ali
    von Itzstein, Mark
    Good, Michael F.
    CLINICAL & TRANSLATIONAL IMMUNOLOGY, 2021, 10 (09)
  • [34] Stimulation of a subset of natural killer T cells by CD103+ DC is required for GM-CSF and protection from pneumococcal infection
    Murray, Mallory Paynich
    Crosby, Catherine M.
    Marcovecchio, Paola
    Hartmann, Nadine
    Chandra, Shilpi
    Zhao, Meng
    Khurana, Archana
    Zahner, Sonja P.
    Clausen, Bjorn E.
    Coleman, Fadie T.
    Mizgerd, Joseph P.
    Mikulski, Zbigniew
    Kronenberg, Mitchell
    CELL REPORTS, 2022, 38 (02):
  • [35] From the Cover: Lung-Specific Overexpression of Constitutively Active IKK2 Induces Pulmonary and Systemic Inflammations but Not Hypothalamic Inflammation and Glucose Intolerance
    Chen, Minjie
    Zhou, Huifen
    Xu, Yanyi
    Qiu, Lianglin
    Hu, Ziying
    Qin, Xiaobo
    Chen, Sufang
    Zhang, Yuhao
    Cao, Qi
    Abu-Amer, Yousef
    Ying, Zhekang
    TOXICOLOGICAL SCIENCES, 2017, 160 (01) : 4 - 14
  • [36] GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTOR (GM-CSF) TREATMENT INDUCES A TH1 RESPONSE IN MICE WITH CHRONIC PSEUDOMONAS AERUGINOSA LUNG INFECTION BY MODULATION OF DENDRITIC CELLS
    Moser, C.
    Jensen, P. Ostrup
    Shirai, R.
    Calum, H.
    Kharazmi, A.
    Hoiby, N.
    PEDIATRIC PULMONOLOGY, 2009, : 297 - 298
  • [37] Tumor-associated GM-CSF overexpression induces immunoinhibitory molecules via STAT3 in myeloid-suppressor cells infiltrating liver metastases
    M Thorn
    P Guha
    M Cunetta
    N J Espat
    G Miller
    R P Junghans
    S C Katz
    Cancer Gene Therapy, 2016, 23 : 188 - 198
  • [38] Tumor-associated GM-CSF overexpression induces immunoinhibitory molecules via STAT3 in myeloid-suppressor cells infiltrating liver metastases
    Thorn, M.
    Guha, P.
    Cunetta, M.
    Espat, N. J.
    Miller, G.
    Junghans, R. P.
    Katz, S. C.
    CANCER GENE THERAPY, 2016, 23 (06) : 188 - 198
  • [39] Baculovirus (CpG motifs) induces an innate immune response and confers protection from lethal influenza virus A and B infection in mice
    Takaku, H
    Abe, T
    Takahashi, H
    Miyano-Kurosaki, N
    ANTIVIRAL RESEARCH, 2006, 70 (01) : A51 - A51
  • [40] GM-CSF and IL-2 induce specific cellular immunity and provide protection against Epstein-Barr virus lymphoproliferative disorder
    Baiocchi, RA
    Ward, JS
    Carrodeguas, L
    Eisenbeis, CF
    Peng, RQ
    Roychowdhury, S
    Vourganti, S
    Sekula, T
    O'Brien, M
    Moeschberger, M
    Caligiuri, MA
    JOURNAL OF CLINICAL INVESTIGATION, 2001, 108 (06): : 887 - 894