Chemoproteomic-Driven Discovery of Covalent PROTACs

被引:3
|
作者
Zhou, Yiqing [1 ]
Xiao, Youli [1 ]
机构
[1] Chinese Acad Sci, Inst Plant Physiol & Ecol, CAS Ctr Excellence Mol Plant Sci, CAS Key Lab Synthet Biol, Shanghai 200032, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1021/acs.biochem.9b00795
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:128 / 129
页数:2
相关论文
共 50 条
  • [21] Protein degradation through covalent inhibitor-based PROTACs
    Xue, Gang
    Chen, Jiahui
    Liu, Lihong
    Zhou, Danli
    Zuo, Yingying
    Fu, Tiancheng
    Pan, Zhengying
    [J]. CHEMICAL COMMUNICATIONS, 2020, 56 (10) : 1521 - 1524
  • [22] Reversible Covalent PROTACs: Novel and Efficient Targeted Degradation Strategy
    Yuan, Minghua
    Chu, Yanan
    Duan, Yongtao
    [J]. FRONTIERS IN CHEMISTRY, 2021, 9
  • [24] Homobivalent, Trivalent, and Covalent PROTACs: Emerging Strategies for Protein Degradation
    Yan, Jianyu
    Li, Tengfei
    Miao, Zhenyuan
    Wang, Pei
    Sheng, Chunquan
    Zhuang, Chunlin
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2022, : 8798 - 8827
  • [25] Efficient Targeted Degradation via Reversible and Irreversible Covalent PROTACs
    Gabizon, Ronen
    Shraga, Amit
    Gehrtz, Paul
    Livnah, Ella
    Shorer, Yamit
    Gurwicz, Neta
    Avram, Liat
    Unger, Tamar
    Aharoni, Hila
    Albeck, Shira
    Brandis, Alexander
    Shulman, Ziv
    Katz, Ben-Zion
    Herishanu, Yair
    London, Nir
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 142 (27) : 11734 - 11742
  • [26] Chemoproteomic Approaches Toward Small Molecule Support in Drug Discovery
    Pham, Victoria
    Crawford, James
    Edgar, Kyle
    Friedman, Lori
    Ghilardi, Nico
    Johnson, Adam
    Katewa, Arna
    Lee, Wendy
    Staben, Steven A.
    Young, Wendy
    Lill, Jennie R.
    [J]. MOLECULAR & CELLULAR PROTEOMICS, 2017, 16 (08) : S49 - S49
  • [27] Editorial: Application of PROTACs as a Novel Strategy for Drug Discovery
    Ibrahim, Hany S.
    Sippl, Wolfgang
    [J]. FRONTIERS IN CHEMISTRY, 2021, 9
  • [28] Chemoproteomic Profiling of Cobalamin-Independent Methionine Synthases in Plants with a Covalent Probe
    Chen, Xin
    Xu, Jingyuan
    Wong, Nai-Kei
    Zhong, Suyun
    Yang, Mengquan
    Liu, Zhen
    Lu, Yan
    Li, Weichao
    Zhou, Yiqing
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 68 (30) : 8050 - 8056
  • [29] Integrating Phenotypic and Chemoproteomic Approaches to Identify Covalent Targets of Dietary Electrophiles in Platelets
    Guan, Ivy A.
    Liu, Joanna S. T.
    Sawyer, Renata C.
    Li, Xiang
    Jiao, Wanting
    Jiramongkol, Yannasittha
    White, Mark D.
    Hagimola, Lejla
    Passam, Freda H.
    Tran, Denise P.
    Liu, Xiaoming
    Schoenwaelder, Simone M.
    Jackson, Shaun P.
    Payne, Richard J.
    Liu, Xuyu
    [J]. ACS CENTRAL SCIENCE, 2024, 10 (02) : 344 - 357
  • [30] Chemoproteomic discovery of lipid kinase inhibitors for immuno-oncology
    Hsu, Ku-Lung
    [J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255