Synthesis of 2-dienylindole, SB 242784, by a three-component palladium-catalyzed coupling reaction

被引:46
|
作者
Yu, MS [1 ]
de Leon, LL [1 ]
McGuire, MA [1 ]
Botha, G [1 ]
机构
[1] SmithKline Beecham Pharmaceut, King Of Prussia, PA 19403 USA
关键词
D O I
10.1016/S0040-4039(98)02161-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The synthesis of SE 242784 using a novel one-pot Castro-Stephens-Suzuki reaction as the key reaction is described. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:9347 / 9350
页数:4
相关论文
共 50 条
  • [41] Palladium-Catalyzed Three-Component Reactions for the Synthesis of Norbornane-Fused Indanes
    Ji, Xiaoming
    Gu, Yichao
    Cheng, Cang
    Wu, Zhuo
    Zhang, Yanghui
    ADVANCED SYNTHESIS & CATALYSIS, 2020, 362 (07) : 1496 - 1501
  • [42] Three-component coupling reaction: Palladium-catalyzed coupling of norbornadiene and iodonium salts or diazonium salts with organostannanes, alkynes, and sodium tetraphenylborate
    Kang, SK
    Kim, JS
    Choi, SC
    Lim, KH
    SYNTHESIS-STUTTGART, 1998, (09): : 1249 - 1251
  • [43] Palladium-Catalyzed Three-Component Coupling Reaction of Allyl Carboxylates, Norbornenes and Diboronates Involving Sequential Olefins Insertion and Borylation Reaction
    Li, Zun
    Zheng, Jia
    Li, Chunsheng
    Wu, Wanqing
    Jiang, Huanfeng
    CHINESE JOURNAL OF CHEMISTRY, 2019, 37 (02) : 140 - 147
  • [44] Palladium-catalyzed intermolecular three-component coupling of organic halides with Alkynes and alkenes: Efficient synthesis of oligoene compounds
    Shibata, Kana
    Satoh, Tetsuya
    Miura, Masahiro
    ADVANCED SYNTHESIS & CATALYSIS, 2007, 349 (14-15) : 2317 - 2325
  • [45] Synthesis of novel substituted poly(arylene-vinylene)s by the palladium-catalyzed three-component coupling polymerization
    Miyaki, N
    Tomita, I
    Kido, J
    Endo, T
    MACROMOLECULES, 1997, 30 (15) : 4504 - 4506
  • [46] Palladium-catalyzed three component coupling on solid support
    Wang, Y
    Huang, TN
    TETRAHEDRON LETTERS, 1999, 40 (32) : 5837 - 5840
  • [47] Palladium-Catalyzed Three-Component Cascade Reaction: Facial Access to Densely Functionalized Indolizines
    Liu, Ren-Rong
    Lu, Chuan-Jun
    Zhang, Ming-Di
    Gao, Jian-Rong
    Jia, Yi-Xia
    CHEMISTRY-A EUROPEAN JOURNAL, 2015, 21 (19) : 7057 - 7060
  • [48] Palladium-catalyzed three-component reaction of N-tosylhydrazone, norbornene and aryl halide
    Hu, Fangdong
    Xia, Ying
    Liu, Zhenxing
    Ma, Chen
    Zhang, Yan
    Wang, Jianbo
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2014, 12 (22) : 3590 - 3593
  • [49] Palladium-catalyzed oxidative three-component tandem annulation reaction: Access to polysubstituted pyrroles
    Bashkar, Mohammad
    Nowrouzi, Najmeh
    MOLECULAR CATALYSIS, 2024, 562
  • [50] A palladium-catalyzed three-component cascade S-transfer reaction in ionic liquids
    Li, Jianxiao
    Wu, Yaodan
    Hu, Miao
    Li, Can
    Li, Meng
    He, Dandan
    Jiang, Huanfeng
    GREEN CHEMISTRY, 2019, 21 (15) : 4084 - 4089