Pharmacological screening of the root extract of Securidaca longepedunculata

被引:0
|
作者
Olajide, AO [1 ]
Awe, SO [1 ]
Makinde, JM [1 ]
机构
[1] Univ Ibadan, Coll Med, Dept Pharmacol & Therapeut, Ibadan, Nigeria
关键词
Securidaca longepedunculata; anti-inflammatory activity; analgesic activity; anticonvulsant activity; phenobarbitone sleeping time;
D O I
暂无
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The methanolic extract of the root of S. longepedunculata was screened for anti-inflammatory, analgesic and anticonvulsant activities, as well as for effects on phenobarbitone sleeping time. The extract produced an inhibition of the carrageenan-induced rat paw oedema, an inhibition of writhings induced by acetic acid, a complete (100%) protection against leptazol-induced convulsion, and a potentiation of the phenobarbitone sleeping time in mice.
引用
收藏
页码:245 / 248
页数:4
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