Soluble Fas and interleukin-6 and interleukin-8 levels in seminal plasma of infertile men

被引：25

作者：

Furuya, Y ^{[1
]}

Akashi, T ^{[1
]}

Fuse, H ^{[1
]}

机构：

[1] Toyama Med & Pharmaceut Univ, Fac Med, Dept Urol, Toyama 9300194, Japan

来源：

ARCHIVES OF ANDROLOGY | 2003年 / 49卷 / 06期

关键词：

interleukin; male infertility; soluble Fas; sperm;

D O I：

10.1080/01485010390219926

中图分类号：

R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

摘要：

The seminal plasma levels of soluble Fas (sFas) and interleukins IL-6 and IL-8 were measured and their relationship with semen qualities was examined. The seminal plasma sFas level in fertile males was significantly higher than that in the infertile group. On the other hand, seminal plasma level of IL-6 was significantly lower in fertile males than in the infertile group. In the infertile group, patients with oligozoospermia had a lower seminal plasma sFas and a higher IL-6 level than those with normal sperm concentration. There was an inverse correlation between IL-6 and sperm concentration in infertile patients. Seminal plasma IL-8 was not correlated with sperm parameters. It would appear that certain kinds of cytokine in the seminal plasma might play an important role in improving semen quality.

引用

页码：449 / 452

页数：4

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