Diastereoselective synthesis of novel 2,5-dioxopyrrolidine derivatives via biocatalytic domino reactions

被引：4
|
作者：
Mohajer, Saadieh [1 ]
Baharfar, Robabeh [1 ]
机构：
[1] Univ Mazandaran, Dept Chem, Babol Sar, Iran
来源：
TURKISH JOURNAL OF CHEMISTRY | 2017年 / 41卷 / 04期
关键词：
Diastereoselective synthesis; 2,5-dioxopyrrolidine derivatives; biocatalytic reactions; ASYMMETRIC ALDOL REACTION; MULTICOMPONENT SYNTHESIS; PYRROLIDINE DERIVATIVES; IMMOBILIZED LIPASE; POTENT; PROMISCUITY; AGONISTS;
D O I：
10.3906/kim-1612-45
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A series of novel 2,5-dioxopyrrolidines were synthesized by the one-pot reaction of coumarin-3-carboxylic acids 1 with thiourea derivatives and alkyl isocyanides in the presence of Fe3O4 NPs @ lipase as heterogeneous reusable nanobiocatalysts with high yields.
引用
收藏
页码：502 / 513
页数：12
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