The reactions of aroylpyruvic acids and their derivatives with o-aminophenyldiphenylmethanol

被引：4
|
作者：
Kolotova, NV [1 ]
Koz'minykh, VO [1 ]
Dolbilkina, EV [1 ]
Koz'minykh, EN [1 ]
机构：
[1] Perm State Pharmaceut Acad, Perm 614051, Russia
来源：
RUSSIAN CHEMICAL BULLETIN | 1998年 / 47卷 / 11期
关键词：
aroylpyruvic acids; methyl aroylpyruvates, 5-arylfuran-2,3-diones, reactions with o-aminophenyldiphenylmethanol; amides of 4-aryl-2-hydroxy-4-oxobut-2-enoic acid; 4,5-dihydrobenzo[e][1,4]oxazepin-3(1H)-ones, 1,1-diphenyl-1H-benzo[d][1,3]oxazines;
D O I：
10.1007/BF02494290
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Aroylpyruvic acids and their methyl esters react with o-aminophenyldiphenylmethanol to form 4-aryl-2-[2-(1-hydroxydiphenylmethyl)phenylamino]-4-oxobut-2-enoic acids and their esters. The alpha-enamino acids obtained undergo intramolecular heterocyclization in the presence of Ac2O to afford substituted 4,5-dihydrobenzo[e] [1,4]oxazepin-3(1H)-ones. The reaction of 5-arylfuran-2,3-diones with o-aminophenyldiphenylmethanol leads to products of decyclization, 2-(1-hydroxydiphenylmethyl)phenylamides of 4-aryl-2-hydroxy-4-oxobut-2-enoic acid, which upon heating in AcOH or Ac2O yield 3-aroylacetyl-1,1-diphenyl-1H-benzo[d][1,3]oxazines.
引用
收藏
页码：2246 / 2248
页数：3
相关论文
共 50 条
  • [41] Synthesis and reactions of fluorous carbobenzyloxy (FCbz) derivatives of α-amino acids
    Curran, DP
    Amatore, M
    Guthrie, D
    Campbell, M
    Go, E
    Luo, ZY
    JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (12): : 4643 - 4647
  • [42] EFFECTS OF SUBSTITUENTS IN REACTIONS OF SULFENYL CHLORIDES WITH DERIVATIVES OF PHOSPHONALLENIC ACIDS
    KHUSAINOVA, NG
    BERDNIKOV, EA
    NAUMOVA, LV
    PUDOVIK, AN
    BULLETIN OF THE ACADEMY OF SCIENCES OF THE USSR DIVISION OF CHEMICAL SCIENCE, 1983, 32 (08): : 1677 - 1683
  • [43] REACTIONS OF HEXAMETHYLDISILAZANES WITH DERIVATIVES OF CYCLIC AND ACYCLIC CARBOXYLIC-ACIDS
    NISHIYAMA, K
    FUJII, M
    SUGAWARA, T
    NIPPON KAGAKU KAISHI, 1990, (05) : 457 - 462
  • [44] POLYFLUORO TRIARYLMETHANES AND THEIR DERIVATIVES .2. REACTIONS OF TRISPENTAFLUOROMETHYLMETHANOL WITH ACIDS
    GERASIMO.TN
    LOKSHINA, EG
    BARKHASH, VA
    VOROZHTS.NN
    JOURNAL OF GENERAL CHEMISTRY USSR, 1967, 37 (06): : 1228 - &
  • [45] REACTIONS OF CARBOXYLIC-ACIDS WITH DICYCLOPENTADIENYL DERIVATIVES OF VANADIUM AND THALLIUM
    RAZUVAEV, GA
    LATYAEVA, VN
    LINEVA, AN
    ZELENEV, SV
    DOKLADY AKADEMII NAUK SSSR, 1974, 216 (03): : 573 - 574
  • [46] REACTIONS OF OZONE .7. OZONIZATION OF FATTY ACIDS AND THEIR DERIVATIVES
    MAGGIOLO, A
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1963, 40 (04) : 161 - &
  • [47] The synthesis and reactions of betaines formed in reactions of tertiary Phosphines with unsaturated carboxylic acids and their derivatives
    Galkin, V. I.
    Bakhtiyarova, Yu. V.
    Sagdieva, R. I.
    Galkina, I. V.
    Cherkasov, R. A.
    HETEROATOM CHEMISTRY, 2006, 17 (06) : 557 - 566
  • [48] GLC OF O-TRIMETHYLSILYL DERIVATIVES OF HEXURONIC ACIDS
    KENNEDY, JF
    ROBERTSON, SM
    STACEY, M
    CARBOHYDRATE RESEARCH, 1976, 49 (JUL) : 243 - 258
  • [49] SYNTHESIS OF O-ACYL DERIVATIVES OF HYDROXAMIC ACIDS
    ARTEMENKO, AI
    ZHURNAL ORGANICHESKOI KHIMII, 1971, 7 (04): : 714 - +
  • [50] One-pot synthesis of dihydroquinolones by sequential reactions of o-aminobenzyl alcohol derivatives with Meldrum's acids
    Arcadi, Antonio
    Calcaterra, Andrea
    Fabrizi, Giancarlo
    Fochetti, Andrea
    Goggiamani, Antonella
    Iazzetti, Antonia
    Marrone, Federico
    Mazzoccanti, Giulia
    Serraiocco, Andrea
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2022, 20 (15) : 3160 - 3173
12345