Synthesis and biological activity of Mannich bases of certain 1,2-pyrazolines

被引：0
|
作者：
Udupi, RH [1 ]
Bhat, AR
Kumar, K
机构：
[1] VL Coll Pharm, Dept Pharmaceut Chem, Raichur 584101, India
[2] Coll Pharmaceut Sci, Manipal 576119, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 1998年 / 8卷 / 02期
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D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The hydroxy pyrazolines were reacted with sulfa drugs and other compounds of biological interest containing free amino group in presence of formaldehyde when Mannich bases of 1,2-pyrazolines IIa-I were obtained. The compounds were characterized by elemental analysis, UV, IR and NMR spectral studies. All the newly synthesized compounds have been screened for antimicrobial activity and few compounds for antiinflammatory activity. Compound Ilk exhibited significant edema inhibiting activity.
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页码：143 / 146
页数：4
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