Protein arginine methyltransferase 5 (PRMT5) is a novel negative regulator of keratinocyte differentiation

被引:0
|
作者
Kanade, S. R. [1 ]
Eckert, R. L. [1 ]
机构
[1] Univ Maryland, Sch Med, Baltimore, MD 21201 USA
关键词
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
358
引用
收藏
页码:S60 / S60
页数:1
相关论文
共 50 条
  • [41] Structural insights into protein arginine symmetric dimethylation by PRMT5
    Sun, Litao
    Wang, Mingzhu
    Lv, Zongyang
    Yang, Na
    Liu, Yingfang
    Bao, Shilai
    Gong, Weimin
    Xu, Rui-Ming
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (51) : 20538 - 20543
  • [42] Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations
    Zhu, Kongkai
    Jiang, Chengshi
    Tao, Hongrui
    Liu, Jingqiu
    Zhang, Hua
    Luo, Cheng
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (09) : 1476 - 1483
  • [43] Novel, small molecule protein arginine methyl transferase 5 (PRMT5) inhibitors for treatment of glioblastoma
    Sivanandhan, D.
    Garapaty, S.
    Seerapu, G. P.
    Das, R.
    Kapoor, N.
    Kar, R.
    Singh, A. K.
    Vadivelu, S.
    Gangaiah, R.
    Mohd, Z.
    Tamizharasan, N.
    Swamy, I.
    Subramaniam, K.
    Tibhe, J.
    Vaidyalingam, K.
    Birudukota, S.
    Thiagaraj, D.
    Burri, R. R.
    Rajagopal, S.
    Rajagopal, S.
    EUROPEAN JOURNAL OF CANCER, 2018, 103 : E120 - E120
  • [44] The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling
    Likhite, Neah
    Jackson, Christopher A.
    Liang, Mao-Shih
    Krzyzanowski, Michelle C.
    Lei, Pedro
    Wood, Jordan F.
    Birkaya, Barbara
    Michaels, Kerry L.
    Andreadis, Stelios T.
    Clark, Stewart D.
    Yu, Michael C.
    Ferkey, Denise M.
    SCIENCE SIGNALING, 2015, 8 (402)
  • [45] Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
    Zhu, Kongkai
    Song, Jia-Li
    Tao, Hong-Rui
    Cheng, Zhi-Qiang
    Jiang, Cheng-Shi
    Zhang, Hua
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (23-24) : 3693 - 3699
  • [46] Developing a first in class of drug to inhibit protein arginine methyltransferase 5 (PRMT5) enzyme dysregulation in glioblastoma multiforme.
    Yan, Fengting
    Gordon, Kate
    Mahasenan, Kiran
    Lustberg, Mark
    Alinari, Lapo
    Earl, Christian T.
    Kaur, Balveen
    Li, Chenglong
    Baiocchi, Robert A.
    CANCER RESEARCH, 2013, 73 (08)
  • [47] In silico analysis of marine natural product for protein arginine methyltransferase 5(PRMT5) inhibitors based on pharmacophore and molecular docking
    Luo, Lianxiang
    Tan, Huiting
    Liao, Yinglin
    JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 41 (22): : 13180 - 13197
  • [48] LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity
    Bonday, Zahid Q.
    Cortez, Guillermo S.
    Grogan, Michael J.
    Antonysamy, Stephen
    Weichert, Ken
    Bocchinfuso, Wayne P.
    Li, Fengling
    Kennedy, Steven
    Li, Binghui
    Mader, Mary M.
    Arrowsmith, Cheryl H.
    Brown, Peter J.
    Eram, Mohammad S.
    Szewczyk, Magdalena M.
    Barsyte-Lovejoy, Dalia
    Vedadi, Masoud
    Guccione, Ernesto
    Campbell, Robert M.
    ACS MEDICINAL CHEMISTRY LETTERS, 2018, 9 (07): : 612 - 617
  • [49] Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the canine model of non-Hodgkin lymphoma
    Renaldo, Kyle A.
    Courtney, Lindsay E.
    Shilo, Konstantin
    Baiocchi, Robert A.
    Kisseberth, William C.
    CANCER RESEARCH, 2018, 78 (13)
  • [50] MTAP deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells
    Kryukov, Gregory V.
    Wilson, Frederick H.
    Ruth, Jason R.
    Paulk, Joshiawa
    Tsherniak, Aviad
    Marlow, Sara E.
    Vazquez, Francisca
    Weir, Barbara A.
    Fitzgerald, Mark E.
    Tanaka, Minoru
    Bielski, Craig M.
    Scott, Justin M.
    Dennis, Courtney
    Cowley, Glenn S.
    Boehm, Jesse S.
    Root, David E.
    Golub, Todd R.
    Clish, Clary B.
    Bradner, James E.
    Hahn, William C.
    Garraway, Levi A.
    SCIENCE, 2016, 351 (6278) : 1214 - 1218