Demyelinating disease in human immunodeficiency virus-infected patients without severe immunodepression

被引：1

作者：

Estebanez-Munoz, Miriam ^{[1
]}

Luisa Montes, Maria ^{[1
,2
]}

Ruiz-Seco, Pilar ^{[1
]}

Royo-Orejas, Aranzazu ^{[2
,3
]}

Gonzalez-Garcia, Juan ^{[1
,2
]}

Ramon Arribas, Jose ^{[1
,2
]}

机构：

[1] Hosp Univ La Paz, Med Interna Serv, Madrid, Spain

[2] Univ Autonoma Madrid, Grp Invest Sindrome Inmunodeficiencia Adquirida S, Inst Invest, Hosp Univ La Paz IdiPAZ,Hosp La Paz, Madrid, Spain

[3] Hosp Univ La Paz, Serv Radiol, Madrid, Spain

来源：

ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA | 2010年 / 28卷 / 09期

关键词：

Demyelinating disease; Progressive multifocal; leukoencephalopathy; Multiple sclerosis; Immunossupression; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; CEREBROSPINAL-FLUID; NEUROINVASION; DIAGNOSIS; BRAIN; DNA; PCR;

D O I：

10.1016/j.eimc.2009.12.007

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Objective: Human immunodeficiency virus (HIV) infected patients who did not have severe immunodepression were analysed for multiple demyelinating lesions. Methods: Patients with a CD4 greater than 200/mu L were selected after a search was made in a computerised data base. Results: Four patients were found, three were co-infected with hepatitis C virus (HCV), with one of them on treatment with peg-interferon alpha-2b and ribavirin. Conclusion: HIV infected patients can develop demyelinating disease without having severe immunodepression, probably favoured by other factors, such as co-infection with HCV. (C) 2009 Elsevier Espana, S.L. All rights reserved.

引用

页码：608 / 611

页数：4

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