Intermolecular tandem Pd-catalyzed cross-coupling [4+4] and [4+2] cycloadditions: A one-pot, five-component assembly of bicyclo[6.4.0]dodecanes

被引：53
|
作者：
Lee, PH [1 ]
Lee, K [1 ]
机构：
[1] Kangwon Natl Univ, Dept Chem, Chunchon 200701, South Korea
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 21期
关键词：
cross-coupling; cycloaddition; indium; palladium; tandem reactions;
D O I：
10.1002/anie.200461957
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) Starting from α-bromovinylarenes, propargyl bromides, and dienophiles, a novel intermolecular tandem Pd-catalyzed cross-coupling/[4+4] and [4+2] cycloaddition sequence provides bicyclo[6.4.0]dodecane derivatives by a rapid synthesis in one reaction vessel. Five components are assembled into one molecule in this process. EWG = electronwithdrawing group. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：3253 / 3256
页数：4
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