Severe fingolimod rebound syndrome after switching to cladribine treatment

被引：10

作者：

Coss-Rovirosa, Fernanda ^{[1
]}

Salado-Burbano, Jorge ^{[1
]}

Casallas-Vanegas, Adriana ^{[2
]}

Elizabeth Caire-Herrera, Laura ^{[3
]}

Gomez-Figueroa, Enrique ^{[1
,2
]}

Flores-Rivera, Jose ^{[1
,2
]}

机构：

[1] Amer British Cowdray Med Ctr, Mexico City, DF, Mexico

[2] Inst Nacl Neurol & Neurocirug, Mexico City, DF, Mexico

[3] Hosp Psiquiatr Infanta Juan N Navarro, Mexico City, DF, Mexico

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2020年 / 40卷

关键词：

Fingolimod; Rebound; Cladribine; Multiple sclerosis; MULTIPLE-SCLEROSIS; DISEASE REACTIVATION;

D O I：

10.1016/j.msard.2020.101938

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We present the clinical and imaging characteristics of a patient whom presented with rebound syndrome after switching from fingolimod to cladribine treatment due to hematologic toxicity. Previous imaging studies had shown a non-aggressive phenotype of the disease, however multiple active tumefactive lesions became evident after beginning treatment with cladribine. The patient responded well to plasmapheresis.

引用

页数：3

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