Molecular structures of some D-homo-6-oxa-8α analogs of steroidal estrogens

被引：3
|
作者：
Shavva, A. G. [1 ]
Starova, G. L. [1 ]
Selivanov, S. I. [1 ]
Morozkina, S. N. [1 ]
机构：
[1] St Petersburg State Univ, Fac Chem, St Petersburg 198504, Petrodvorets, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2008年 / 44卷 / 02期
关键词：
steroidal estrogen analogs; molecular structure; molecular modeling;
D O I：
10.1007/s10593-008-0036-2
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
By X-ray crystallographic analysis and NMR spectroscopy it was demonstrated that the conformations of several D-homo-6-oxa-8 alpha analogs of steroidal estrogens are similar in the crystal and in solution. The distances between the hydrogen atoms in these molecules, calculated by the ab initio and MM+ methods, correspond to the experimental data.
引用
收藏
页码：148 / 152
页数：5
相关论文
共 50 条
  • [1] Molecular structures of some D-homo-6-oxa-8α analogs of steroidal estrogens
    A. G. Shavva
    G. L. Starova
    S. I. Selivanov
    S. N. Morozkina
    [J]. Chemistry of Heterocyclic Compounds, 2008, 44 : 148 - 152
  • [2] Synthesis and biological properties of D-homo-6-oxa-8α-analogues of steroid estrogens
    Shavva, A. G.
    Morozkina, S. N.
    Ishchenko, I. V.
    Eliseev, I. I.
    Selivanov, S. I.
    Abusalimov, Sh. N.
    Selivanov, S. S.
    Kameneva, I. Yu.
    Eshchenko, N. D.
    [J]. RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2007, 33 (03) : 288 - 292
  • [3] Synthesis and biological properties of D-homo-6-oxa-8α-analogues of steroid estrogens
    A. G. Shavva
    S. N. Morozkina
    I. V. Ishchenko
    I. I. Eliseev
    S. I. Selivanov
    Sh. N. Abusalimov
    S. S. Selivanov
    I. Yu. Kameneva
    N. D. Eshchenko
    [J]. Russian Journal of Bioorganic Chemistry, 2007, 33 : 288 - 292
  • [4] NEW VARIANT OF THE SYNTHESIS OF D-HOMO-6-OXA-8α-ANALOGS OF STEROID ESTROGENS CONTAINING A β-METHYL GROUP AT C-7
    Morozkina, S. N.
    Chentsova, A. S.
    Hasan, T. Yu.
    Selivanov, S. I.
    Shavarda, A. L.
    Shavva, A. G.
    [J]. CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2009, 45 (09) : 1144 - 1146
  • [5] New variant of the synthesis of D-homo-6-oxa-8α-analogs of steroid estrogens containing a β-methyl group at C-7
    S. N. Morozkina
    A. S. Chentsova
    T. Yu. Hasan
    S. I. Selivanov
    A. L. Shavarda
    A. G. Shavva
    [J]. Chemistry of Heterocyclic Compounds, 2009, 45 : 1144 - 1146
  • [6] Synthesis and Molecular Structure of D-Homo-B-nor-8α Analogs of Steroidal Estrogens
    Shavva, A. G.
    Antimonova, O. I.
    Baigozin, D. V.
    Starova, G. L.
    Selivanov, S. I.
    Morozkina, S. N.
    [J]. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2010, 46 (10) : 1511 - 1516
  • [7] Synthesis and Molecular Structure of D-Homo-B-nor-8α Analogs of Steroidal Estrogens
    A. G. Shavva
    O. I. Antimonova
    D. V. Baigozin
    G. L. Starova
    S. I. Selivanov
    S. N. Morozkina
    [J]. Russian Journal of Organic Chemistry, 2010, 46 : 1511 - 1516
  • [8] Synthesis and biological activity of some 8α-analogs of steroidal estrogens
    Morozkina, S. N.
    Abusalimov, Sh. N.
    Selivanov, S. I.
    Shavva, A. G.
    [J]. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2013, 49 (04) : 603 - 609
  • [9] Synthesis and biological activity of some 8α-analogs of steroidal estrogens
    S. N. Morozkina
    Sh. N. Abusalimov
    S. I. Selivanov
    A. G. Shavva
    [J]. Russian Journal of Organic Chemistry, 2013, 49 : 603 - 609
  • [10] INVESTIGATION OF THE CONFORMATIONAL TRANSFORMATIONS IN SOME 7α-METHYL6-OXA-14β-ANALOGS OF STEROIDAL ESTROGENS BY NMR SPECTROSCOPY
    Selivanov, S. I.
    Morozkina, S. N.
    Chentsova, A. S.
    Shavva, A. G.
    [J]. CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2008, 44 (06) : 654 - 665
12345