MLH1 and PMS2 protein expression in 103 colorectal carcinomas with MLH1 promoter methylation and without MLH1 or PMS2 germline mutation

被引：0
|
作者：
Mahooti, S [1 ]
Hampel, H [1 ]
LaJeunesse, J [1 ]
Sotamaa, K [1 ]
de la Chapelle, A [1 ]
Frankel, WL [1 ]
机构：
[1] Ohio State Univ, Med Ctr, Columbus, OH 43210 USA
来源：
MODERN PATHOLOGY | 2006年 / 19卷
关键词：
D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
512
引用
收藏
页码：113A / 113A
页数：1
相关论文
共 50 条
  • [41] Methylation of the MLH1 promoter results in loss of MLH1 expression and drug resistance in ovarian tumour cells
    Strathdee, G
    MacKean, M
    Brown, R
    [J]. BRITISH JOURNAL OF CANCER, 1998, 78 : 20 - 20
  • [42] A Single Institution Cohort of Isolated PMS2 Loss in Endometrial Carcinoma Highlights Difficult MLH1 Patterns, Presence of MLH1 Promoter Hypermethylation, and Low Genetic Testing Follow Through Rates
    Kozman, Diana
    Azzato, Elizabeth
    Garg, Karuna
    Joehlin-Price, Amy
    [J]. LABORATORY INVESTIGATION, 2024, 104 (03) : S1185 - S1186
  • [43] Saccharomyces cerevisiae pms2 mutations are alleles of MLH1, and pms2-2 corresponds to a hereditary nonpolyposis colorectal carcinoma-causing missense mutation
    Jeyaprakash, A
    DasGupta, R
    Kolodner, R
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 1996, 16 (06) : 3008 - 3011
  • [44] Germline MLH1 Mutations Are Frequently Identified in Lynch Syndrome Patients With Colorectal and Endometrial Carcinoma Demonstrating Isolated Loss of PMS2 Immunohistochemical Expression
    Dudley, Beth
    Brand, Randall E.
    Thull, Darcy
    Bahary, Nathan
    Nikiforova, Marina N.
    Pai, Reetesh K.
    [J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 2015, 39 (08) : 1114 - 1120
  • [45] Isolated MLH1 Loss by Immunohistochemistry Because of Benign Germline MLH1 Polymorphisms
    Bosch, Dustin E.
    Yeh, Matthew M.
    Salipante, Stephen J.
    Jacobson, Angela
    Cohen, Stacey A.
    Konnick, Eric Q.
    Paulson, Vera A.
    [J]. JCO PRECISION ONCOLOGY, 2022, 6
  • [46] MLH1 promoter hypermethylation: are you absolutely sure about the absence of MLH1 germline mutation? About a new case
    Caroline Kientz
    Fabienne Prieur
    Alix Clemenson
    Marie-Odile Joly
    Marie-Laure Stachowicz
    Jessie Auclair
    Valéry Attignon
    Renaud Schiappa
    Qing Wang
    [J]. Familial Cancer, 2020, 19 : 11 - 14
  • [47] MLH1 promoter hypermethylation: are you absolutely sure about the absence of MLH1 germline mutation? About a new case
    Kientz, Caroline
    Prieur, Fabienne
    Clemenson, Alix
    Joly, Marie-Odile
    Stachowicz, Marie-Laure
    Auclair, Jessie
    Attignon, Valery
    Schiappa, Renaud
    Wang, Qing
    [J]. FAMILIAL CANCER, 2020, 19 (01) : 11 - 14
  • [48] Absence of PMS2 mutations in colon-CFR participants whose colorectal cancers demonstrate unexplained loss of MLH1 expression
    Clendenning, M.
    Macrae, F. A.
    Walsh, M. D.
    Walters, R. J.
    Thibodeau, S. N.
    Gunawardena, S. R.
    Potter, J. D.
    Haile, R. W.
    Gallinger, S.
    Hopper, J. L.
    Jenkins, M. A.
    Rosty, C.
    Young, J. P.
    Buchanan, D. D.
    [J]. CLINICAL GENETICS, 2013, 83 (06) : 591 - 593
  • [49] Punctate Pattern Nuclear MLH1 Immunoexpression Without Classic Nuclear MLH1 Staining is an Artifact in MMR Deficient Endometrial Cancer that Merits MLH1 Promoter Methylation Testing
    Bhardwaj, Swati
    Rabban, Joseph
    [J]. LABORATORY INVESTIGATION, 2023, 103 (03) : S861 - S861
  • [50] Correlation of Age-Related Prevalence of Mlh1/Pms2 Deficiency in Early and Late-Onset Colorectal Cancer
    Yang, Juliana F.
    Noffsinger, Amy
    Yang, Qinghua
    [J]. GASTROINTESTINAL ENDOSCOPY, 2017, 85 (05) : AB399 - AB400
12345