MLH1 and PMS2 protein expression in 103 colorectal carcinomas with MLH1 promoter methylation and without MLH1 or PMS2 germline mutation

被引:0
|
作者
Mahooti, S [1 ]
Hampel, H [1 ]
LaJeunesse, J [1 ]
Sotamaa, K [1 ]
de la Chapelle, A [1 ]
Frankel, WL [1 ]
机构
[1] Ohio State Univ, Med Ctr, Columbus, OH 43210 USA
关键词
D O I
暂无
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
512
引用
收藏
页码:113A / 113A
页数:1
相关论文
共 50 条
  • [1] MLH1 and PMS2 protein expression in 103 colorectal carcinomas with MLH1 promoter methylation and without MLH1 or PMS2Germline mutation
    Mahooti, S
    Hampel, H
    LaJeunesse, J
    Sotamaa, K
    de la Chapelle, A
    Frankel, WL
    [J]. LABORATORY INVESTIGATION, 2006, 86 : 113A - 113A
  • [2] Assessing pathogenicity of MLH1 variants by co-expression of human MLH1 and PMS2 genes in yeast
    Vogelsang, Matjaz
    Comino, Aleksandra
    Zupanec, Neja
    Hudler, Petra
    Komel, Radovan
    [J]. BMC CANCER, 2009, 9
  • [3] Immunohistochemistry for MLH1, MSH2, MSH6, and PMS2 identifies most cases with germline HNPCC mutations and methylation of the MLH1 promoter
    Frankel, WL
    Hampel, H
    Nakagawa, H
    Morrison, C
    de la Chapelle, A
    [J]. LABORATORY INVESTIGATION, 2003, 83 (01) : 118A - 118A
  • [4] Immunohistochemistry for MLH1, MSH2, MSH6, and PMS2 identifies most cases with germline HNPCC mutations and methylation of the MLH1 promoter
    Frankel, WL
    Hampel, H
    Nakagawa, H
    Morrison, C
    de la Chapelle, A
    [J]. MODERN PATHOLOGY, 2003, 16 (01) : 118A - 118A
  • [5] Dimerization of MLH1 and PMS2 limits nuclear localization of MutLα
    Wu, XS
    Platt, JL
    Cascalho, M
    [J]. MOLECULAR AND CELLULAR BIOLOGY, 2003, 23 (09) : 3320 - 3328
  • [6] MLH1/PMS2-deficient Endometrial Carcinomas in a Universally Screened Population: MLH1 Hypermethylation and Germline Mutation Status
    Kurpiel, Brett
    Thomas, Martha S.
    Mubeen, Mansoor
    Ring, Kari L.
    Modesitt, Susan C.
    Moskaluk, Christopher A.
    Mills, Anne M.
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2022, 41 (01) : 1 - 11
  • [7] Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2
    Cannavo, Elda
    Gerrits, Bertran
    Marra, Giancarlo
    Schlapbach, Ralph
    Jiricny, Josef
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (05) : 2976 - 2986
  • [8] MLH1, PMS2 And MSH6 Loss; Sporadic, Germline or Both?
    Zia, Shereen
    Hein, Ashley
    Krishnan, Ramakrishnan
    Dumur, Catherine
    Khoury, Joseph
    Pradhan, Dinesh
    [J]. LABORATORY INVESTIGATION, 2024, 104 (03) : S869 - S870
  • [9] Ovarian metastasis from uveal melanoma with MLH1/PMS2 protein loss in a patient with germline MLH1 mutated Lynch syndrome: consequence or coincidence?
    João Lobo
    Carla Pinto
    Micaela Freitas
    Manuela Pinheiro
    Rámon Vizcaino
    Esther Oliva
    Manuel R. Teixeira
    Carmen Jerónimo
    Carla Bartosch
    [J]. Virchows Archiv, 2017, 470 : 347 - 352
  • [10] Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort
    Rosty, Christophe
    Clendenning, Mark
    Walsh, Michael D.
    Eriksen, Stine V.
    Southey, Melissa C.
    Winship, Ingrid M.
    Macrae, Finlay A.
    Boussioutas, Alex
    Poplawski, Nicola K.
    Parry, Susan
    Arnold, Julie
    Young, Joanne P.
    Casey, Graham
    Haile, Robert W.
    Gallinger, Steven
    Le Marchand, Loic
    Newcomb, Polly A.
    Potter, John D.
    DeRycke, Melissa
    Lindor, Noralane M.
    Thibodeau, Stephen N.
    Baron, John A.
    Win, Aung Ko
    Hopper, John L.
    Jenkins, Mark A.
    Buchanan, Daniel D.
    [J]. BMJ OPEN, 2016, 6 (02):