Risperidone and clozapine combination for the treatment of refractory schizophrenia
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作者:
Morera, AL
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Univ La Laguna, Dept Med Interna & Psiquiatria, Fac Med, La Laguna 38320, Tenerife, SpainUniv La Laguna, Dept Med Interna & Psiquiatria, Fac Med, La Laguna 38320, Tenerife, Spain
Morera, AL
[1
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Barreiro, P
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机构:Univ La Laguna, Dept Med Interna & Psiquiatria, Fac Med, La Laguna 38320, Tenerife, Spain
Barreiro, P
Cano-Muñoz, JL
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机构:Univ La Laguna, Dept Med Interna & Psiquiatria, Fac Med, La Laguna 38320, Tenerife, Spain
Cano-Muñoz, JL
机构:
[1] Univ La Laguna, Dept Med Interna & Psiquiatria, Fac Med, La Laguna 38320, Tenerife, Spain
Clozapine is the most widely used antipsychotic drug for the treatment of refractory schizophrenia. Here we report the case of two residual schizophrenic patients refractory to conventional antipsychotics who showed a poor response to atypical antipsychotics. The combination of risperidone and clozapine produced a noticeable improvement in the patients' clinical status and a shortening of the treatment response latency.