Inferring genome-scale rearrangement phylogeny and ancestral gene order:: a Drosophila case study
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作者:
Bhutkar, Arjun
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Boston Univ, Biomol Engn Res Ctr, Boston, MA 02215 USA
Harvard Univ, Dept Mol & Cell Biol, Cambridge, MA 02138 USABoston Univ, Biomol Engn Res Ctr, Boston, MA 02215 USA
Bhutkar, Arjun
[1
,2
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Gelbart, William M.
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Harvard Univ, Dept Mol & Cell Biol, Cambridge, MA 02138 USABoston Univ, Biomol Engn Res Ctr, Boston, MA 02215 USA
Gelbart, William M.
[2
]
Smith, Temple F.
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Boston Univ, Biomol Engn Res Ctr, Boston, MA 02215 USABoston Univ, Biomol Engn Res Ctr, Boston, MA 02215 USA
Smith, Temple F.
[1
]
机构:
[1] Boston Univ, Biomol Engn Res Ctr, Boston, MA 02215 USA
[2] Harvard Univ, Dept Mol & Cell Biol, Cambridge, MA 02138 USA
A simple, fast, and biologically inspired computational approach for inferring genome-scale rearrangement phylogeny and ancestral gene order has been developed. This has been applied to eight Drosophila genomes. Existing techniques are either limited to a few hundred markers or a small number of taxa. This analysis uses over 14,000 genomic loci and employs discrete elements consisting of pairs of homologous genetic elements. The results provide insight into evolutionary chromosomal dynamics and synteny analysis, and inform speciation studies.
机构:
Lawrence Berkeley Natl Lab, US Dept Energy Joint Genome Inst, Berkeley, CA USAStockholm Univ, Dept Ecol Environm & Plants Sci, Stockholm, Sweden
Barry, Kerrie
Miller, Andrew N.
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Univ Illinois, Illinois Nat Hist Survey, Urbana, IL USAStockholm Univ, Dept Ecol Environm & Plants Sci, Stockholm, Sweden
Miller, Andrew N.
Grigoriev, Igor, V
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Lawrence Berkeley Natl Lab, US Dept Energy Joint Genome Inst, Berkeley, CA USA
Univ Calif Berkeley, Dept Plant & Microbial Biol, Berkeley, CA USAStockholm Univ, Dept Ecol Environm & Plants Sci, Stockholm, Sweden
Grigoriev, Igor, V
Debuchy, Robert
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Univ Paris Saclay, Inst Integrat Biol Cell, Gif Sur Yvette, FranceStockholm Univ, Dept Ecol Environm & Plants Sci, Stockholm, Sweden
Debuchy, Robert
Gladieux, Pierre
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Univ Montpellier, PHIM Plant Hlth Inst, Montpellier, FranceStockholm Univ, Dept Ecol Environm & Plants Sci, Stockholm, Sweden
Gladieux, Pierre
Thoren, Markus Hiltunen
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Stockholm Univ, Dept Ecol Environm & Plants Sci, Stockholm, Sweden
Royal Swedish Acad Sci, Stockholm, SwedenStockholm Univ, Dept Ecol Environm & Plants Sci, Stockholm, Sweden
Thoren, Markus Hiltunen
Johannesson, Hanna
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Stockholm Univ, Dept Ecol Environm & Plants Sci, Stockholm, Sweden
Royal Swedish Acad Sci, Stockholm, SwedenStockholm Univ, Dept Ecol Environm & Plants Sci, Stockholm, Sweden
机构:
Univ Ottawa, Dept Math & Stat, 150 Louis Pasteur Pvt, Ottawa, ON K1N 6N5, CanadaUniv Ottawa, Dept Math & Stat, 150 Louis Pasteur Pvt, Ottawa, ON K1N 6N5, Canada
Xu, Qiaoji
Sankoff, David
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Univ Ottawa, Dept Math & Stat, 150 Louis Pasteur Pvt, Ottawa, ON K1N 6N5, CanadaUniv Ottawa, Dept Math & Stat, 150 Louis Pasteur Pvt, Ottawa, ON K1N 6N5, Canada
机构:
Univ Wisconsin, US DOE, JF Crow Inst Study Evolut,Lab Genet, Great Lakes Bioenergy Res Ctr,Ctr Genom Sci Innov, Madison, WI 53706 USAVanderbilt Univ, Dept Biol Sci, Nashville, TN 37235 USA
Hittinger, Chris Todd
Shen, Xing-Xing
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Zhejiang Univ, State Key Lab Rice Biol, Hangzhou 310058, Peoples R China
Zhejiang Univ, Minist Agr, Inst Insect Sci, Key Lab Mol Biol Crop Pathogens & Insects, Hangzhou 310058, Peoples R ChinaVanderbilt Univ, Dept Biol Sci, Nashville, TN 37235 USA
机构:
Massey Univ, Allan Wilson Ctr Mol Ecol & Evolut, Palmerston North, New ZealandMassey Univ, Allan Wilson Ctr Mol Ecol & Evolut, Palmerston North, New Zealand
Phillips, MJ
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Delsuc, F
Penny, D
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Massey Univ, Allan Wilson Ctr Mol Ecol & Evolut, Palmerston North, New ZealandMassey Univ, Allan Wilson Ctr Mol Ecol & Evolut, Palmerston North, New Zealand
机构:
Massey Univ, Inst Fundamental Sci, Allan Wilson Ctr, Palmerston North, New ZealandMassey Univ, Inst Fundamental Sci, Allan Wilson Ctr, Palmerston North, New Zealand
Holland, BR
Jermiin, LS
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机构:Massey Univ, Inst Fundamental Sci, Allan Wilson Ctr, Palmerston North, New Zealand
Jermiin, LS
Moulton, V
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机构:Massey Univ, Inst Fundamental Sci, Allan Wilson Ctr, Palmerston North, New Zealand