Baclofen, a treatment for chronic hiccup

被引：32
|
作者：
Walker, P [1 ]
Watanabe, S [1 ]
Bruera, E [1 ]
机构：
[1] Grey Nuns Community Hosp & Hlth Ctr, Palliat Care Program, Edmonton, AB T6L 5X8, Canada
来源：
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT | 1998年 / 16卷 / 02期
关键词：
hiccup; baclofen; singultus; hiccough;
D O I：
10.1016/S0885-3924(98)00039-6
中图分类号：
R19 [保健组织与事业（卫生事业管理）];
学科分类号：
摘要：
The efficacy of baclofen in the treatment of chronic hiccup is demonstrated in true cases. These cases highlight the present state of knowledge related to hiccup. This discussion focuses on the definition and classification of hiccup, etiologies, postulated theories to explain its function, the few studies performed to date, and non-pharmacologic and pharmacologic treatment. Baclofen appears to be the agent most efficacious in the treatment of chronic hiccup. Its commonest side effect is sedation; insomnia, dizziness, weakness, ataxia, and confusion also can occur. Following regular use, abrupt discontinuation can. lend to withdrawal symptoms, such as seizure, and gradual discontinuation is recommended. J Pain Symptom Manage 1998;16:125-132. (C) U.S. Cancer Pain Relief Committee, 1998.
引用
收藏
页码：125 / 132
页数：8
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