Cerebral Small Vessel Disease

被引：220
|
作者：
Li, Qian [1 ,2 ]
Yang, Yang [3 ]
Reis, Cesar [4 ]
Tao, Tao [3 ]
Li, Wanwei [1 ,2 ]
Li, Xiaogang [3 ]
Zhang, John H. [4 ,5 ]
机构：
[1] Army Med Univ, Affiliated Hosp 3, Dept Pediat, Chongqing, Peoples R China
[2] Army Med Univ, Field Surg Inst, Chongqing, Peoples R China
[3] Southwest Med Univ, Affiliated Hosp, Dept Neurol, Luzhou, Sichuan, Peoples R China
[4] Loma Linda Univ, Sch Med, Dept Physiol & Pharmacol, Loma Linda, CA USA
[5] Loma Linda Univ, Sch Med, Dept Anesthesiol, Loma Linda, CA USA
来源：
CELL TRANSPLANTATION | 2018年 / 27卷 / 12期
关键词：
Cerebral small vessel disease; arteriolosclerosis; cerebral amyloid angiopathy; neuroimaging; MRI; stroke syndrome; dementia; TRANSIENT ISCHEMIC ATTACK; WHITE-MATTER HYPERINTENSITIES; RECENT LACUNAR STROKE; AMYLOID ANGIOPATHY; INTRACEREBRAL HEMORRHAGE; COGNITIVE IMPAIRMENT; MRI CHARACTERISTICS; ALZHEIMER-DISEASE; DIFFUSION TENSOR; BLOOD-FLOW;
D O I：
10.1177/0963689718795148
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Cerebral small vessel disease (CSVD) is composed of several diseases affecting the small arteries, arterioles, venules, and capillaries of the brain, and refers to several pathological processes and etiologies. Neuroimaging features of CSVD include recent small subcortical infarcts, lacunes, white matter hyperintensities, perivascular spaces, microbleeds, and brain atrophy. The main clinical manifestations of CSVD include stroke, cognitive decline, dementia, psychiatric disorders, abnormal gait, and urinary incontinence. Currently, there are no specific preventive or therapeutic measures to improve this condition. In this review, we will discuss the pathophysiology, clinical aspects, neuroimaging, progress of research to treat and prevent CSVD and current treatment of this disease.
引用
收藏
页码：1711 / 1722
页数：12
相关论文
共 50 条
  • [31] Genetics of common cerebral small vessel disease
    Bordes, Constance
    Sargurupremraj, Muralidharan
    Mishra, Aniket
    Debette, Stephanie
    [J]. NATURE REVIEWS NEUROLOGY, 2022, 18 (02) : 84 - 101
  • [32] Advanced Neuroimaging of Cerebral Small Vessel Disease
    Blair G.W.
    Hernandez M.V.
    Thrippleton M.J.
    Doubal F.N.
    Wardlaw J.M.
    [J]. Current Treatment Options in Cardiovascular Medicine, 2017, 19 (7)
  • [33] Advanced MRI in cerebral small vessel disease
    van den Brink, Hilde
    Doubal, Fergus N.
    Duering, Marco
    [J]. INTERNATIONAL JOURNAL OF STROKE, 2023, 18 (01) : 28 - 35
  • [34] Hypertensive cerebral small vessel disease and stroke
    Lammie, GA
    [J]. BRAIN PATHOLOGY, 2002, 12 (03) : 358 - 370
  • [35] Update of Immunosenescence in Cerebral Small Vessel Disease
    Jian, Banghao
    Hu, Mengyan
    Cai, Wei
    Zhang, Bingjun
    Lu, Zhengqi
    [J]. FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [36] Genetics of common cerebral small vessel disease
    Constance Bordes
    Muralidharan Sargurupremraj
    Aniket Mishra
    Stéphanie Debette
    [J]. Nature Reviews Neurology, 2022, 18 : 84 - 101
  • [37] Antiplatelet Therapy in Cerebral Small Vessel Disease
    Bouasquevisque, Danielle de Sa
    Benavente, Oscar R.
    Shoamanesh, Ashkan
    [J]. CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS, 2019, 19 (09)
  • [38] Cerebral Small Vessel Disease: A Bibliometric Analysis
    Ma, Wei
    Yang, Yi-Bao
    Xie, Ting-Ting
    Xu, Yi
    Liu, Na
    Mo, Xue-Ni
    [J]. JOURNAL OF MOLECULAR NEUROSCIENCE, 2022, 72 (11) : 2345 - 2359
  • [39] Arterial Stiffness and Cerebral Small Vessel Disease
    Zhai, Fei-Fei
    Ye, Yi-Cong
    Chen, Si-Yu
    Ding, Fa-Ming
    Han, Fei
    Yang, Xing-Lin
    Wang, Quan
    Zhou, Li-Xin
    Ni, Jun
    Yao, Ming
    Li, Ming-Li
    Jin, Zheng-Yu
    Cui, Li-Ying
    Zhang, Shu-Yang
    Zhu, Yi-Cheng
    [J]. FRONTIERS IN NEUROLOGY, 2018, 9
  • [40] Cerebral vasomotor reactivity in small vessel disease
    Lee, Y.
    Kim, B.
    [J]. JOURNAL OF THE NEUROLOGICAL SCIENCES, 2009, 283 (1-2) : 279 - 279
12345