Visual-X2: interactive visualization and analysis tool for protein crystallization

被引:1
|
作者
Subedi, Suraj [1 ]
Dinc, Imren [2 ]
Tran, Truong X. [1 ]
Sharma, Diwas [1 ]
Shrestha, Buddha R. [1 ]
Pusey, Marc L. [3 ,4 ]
Aygun, Ramazan S. [1 ]
机构
[1] Univ Alabama, Dept Comp Sci, Data Media Lab, Huntsville, AL 35899 USA
[2] Troy Univ, Montgomery, AL USA
[3] iXpressGenes Inc, 601 Genome Way, Huntsville, AL USA
[4] Univ Alabama, Dept Chem, Huntsville, AL 35899 USA
基金
美国国家卫生研究院;
关键词
Protein crystallization; Screening analysis; Visualization of crystallization trials; IMAGES;
D O I
10.1007/s13721-020-0220-6
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
In high-throughput systems, the crystallization experiments require the inspection and analysis of a large number of trial images. The visualization and analysis tools are needed to view and analyze the experimental results, and recommend novel crystalline conditions by analyzing prior results. It is essential to integrate all these components into a single system. Therefore, we developed Visual-X2, an interactive visualization software developed to aid the user for quick and efficient visualization and analysis of the results of the experiments. Visual-X2 has a number of useful features for visualization and analysis: dual plate view (thumbnail and symbolic), detailed well view with scoring option, multiple-scan and time-course views, support for screening analysis based on multiple screens, three novel screen analysis methods (associative experimental design, GenScreen, and novelty methods), and generating pipetting file with a family of conditions varying concentrations based on stock concentration.
引用
收藏
页数:13
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