This paper is focused on the analysis of spillover benefits of the ongoing R&D program on nuclear fusion in Korea. An empirical analysis was conducted on the economic spillover effects of nuclear fusion research and development (R&D) program by investigating cases of actual participating enterprises. The 24 representative enterprises were selected from about 250 enterprises that participated in the KSTAR and ITER projects. The analysis showed that the effect of increasing sales was a total of 1,538,600M KRW in the 24 enterprises that participated in the KSTAR and ITER projects; about 527 human resources have been fostered in industrial enterprises. Additionally, network analysis results show some cases in which the participating enterprises have extended their businesses into international and domestic fields of nuclear fusion and particle accelerators as well as into private markets. (C) 2017 Elsevier B.V. All rights reserved.